Involvement of Protein Kinase Mζ in the Maintenance of Long-Term Memory for Taste Aversion Learning in Young Chicks

Verfasser / Beitragende:
[A. Tiunova, D. Bezryadnov, K. Anokhin]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/5(2015-03-01), 592-594
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2813-0  |2 doi 
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245 0 0 |a Involvement of Protein Kinase Mζ in the Maintenance of Long-Term Memory for Taste Aversion Learning in Young Chicks  |h [Elektronische Daten]  |c [A. Tiunova, D. Bezryadnov, K. Anokhin] 
520 3 |a The effects of an inhibitor of protein kinase Mζ on long-term memory were studied using the model of taste aversion in newborn chicks. Memory was impaired by intracerebral injection of 10 or 20 nmol of ζ-inhibiting peptide 24 h after training. Memory impairment was found 2 h after peptide administration, and repeated examination 24 h after treatment showed no recovery. Memory impairment was not observed 24 h after inhibitor administration if the testing 2 h after treatment was not performed. The results indicate the contribution of protein kinase Mζ in the maintenance of long-term memory in the avian brain. These data confirm the hypothesis of several authors that inhibition of protein kinase Mζ does not abolish memory, but rather interacts with processes of memory retrieval and/or reconsolidation. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a protein kinase Mζ  |2 nationallicence 
690 7 |a memory  |2 nationallicence 
690 7 |a taste aversion  |2 nationallicence 
690 7 |a birds  |2 nationallicence 
700 1 |a Tiunova  |D A.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Bezryadnov  |D D.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Anokhin  |D K.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tiunova  |D A.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bezryadnov  |D D.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Anokhin  |D K.  |u P. K. Anokhin Research Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/5(2015-03-01), 592-594  |x 0007-4888  |q 158:5<592  |1 2015  |2 158  |o 10517