caa a22 4500 605538530 CHVBK 20210128100902.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10517-015-2817-9 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2817-9 Behavioral, Hormonal, and Neurotransmitter Reactions to Stress in Adult Rats with a History of High IL-1β Content in the Early Postnatal Ontogeny [Elektronische Daten] [O. Zubareva, A. Schwartz, L. Khnychenko, A. Ishchenko, A. Simbirtsev, V. Klimenko] Behavioral, hormonal, and neurotransmitter reactions to foot shock were studied in adult rats treated with IL-1β during week 3 of life. After stress, these animals differed from controls treated with saline by high levels of dopamine, serotonin, and 5-hydroxy-indolacetic acid in the hypothalamus. In contrast to controls, they developed a significant stress-induced increase of blood corticosterone level and exhibited lesser motor and exploratory activities in the open field test. Springer Science+Business Media New York, 2015 interleukin-1β nationallicence early postnatal ontogeny nationallicence stress nationallicence behavior nationallicence monoamines nationallicence Zubareva O. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut Schwartz A. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut Khnychenko L. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut Ishchenko A. State Research Institute of Extrapure Biopreparations, Federal Biomedical Agency of Russia, St. Petersburg, Russia aut Simbirtsev A. State Research Institute of Extrapure Biopreparations, Federal Biomedical Agency of Russia, St. Petersburg, Russia aut Klimenko V. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/5(2015-03-01), 607-610 0007-4888 158:5<607 2015 158 10517 https://doi.org/10.1007/s10517-015-2817-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2817-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zubareva O. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Schwartz A. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Khnychenko L. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Ishchenko A. State Research Institute of Extrapure Biopreparations, Federal Biomedical Agency of Russia, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Simbirtsev A. State Research Institute of Extrapure Biopreparations, Federal Biomedical Agency of Russia, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Klimenko V. Research Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/5(2015-03-01), 607-610 0007-4888 158:5<607 2015 158 10517