Expression of Vascular Endothelial Growth Factor (VEGF-A) in Rat Mandibular Salivary Gland during Paraneoplastic Process and Treatment with Cyclophosphamide and Melatonin
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2833-9 |2 doi |
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| 245 | 0 | 0 | |a Expression of Vascular Endothelial Growth Factor (VEGF-A) in Rat Mandibular Salivary Gland during Paraneoplastic Process and Treatment with Cyclophosphamide and Melatonin |h [Elektronische Daten] |c [E. Ovsyanko, A. Kulishenko, E. Lushnikova, A. Vinogradov, I. Zhurakovskii, M. Pustovetova, Ya. Ovsyanko] |
| 520 | 3 | |a Expression of VEGF-A in Walker 256 carcinosarcoma and mandibular salivary gland of rats during paraneoplastic process and various regimens of chemotherapy with melatonin and cyclophosphamide were studied by immunohistochemical methods. VEGF-A expression increased in the tumor node and salivary gland after monotherapy with melatonin and cyclophosphamide during progression of tumor growth and paraneoplastic syndrome. A decrease in VEGF-A expression in the tumor node and salivary gland was found after monotherapy with melatonin and cyclophosphamide and, especially, after combined treatment, which proves maximum therapeutic efficiency of combined administration of chemical agents with various mechanisms of action. Overexpression of VEGF-A in the mandibular salivary gland can have diagnostic and predictive value in early diagnostics of neoplasms. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Walker 256 carcinosarcoma |2 nationallicence | |
| 690 | 7 | |a vascular endothelial growth factor |2 nationallicence | |
| 690 | 7 | |a mandibular salivary gland |2 nationallicence | |
| 690 | 7 | |a melatonin |2 nationallicence | |
| 690 | 7 | |a cyclophosphamide |2 nationallicence | |
| 700 | 1 | |a Ovsyanko |D E. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Kulishenko |D A. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Lushnikova |D E. |u Research Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Vinogradov |D A. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Zhurakovskii |D I. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Pustovetova |D M. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Ovsyanko |D Ya |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 676-680 |x 0007-4888 |q 158:5<676 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2833-9 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2833-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ovsyanko |D E. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kulishenko |D A. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lushnikova |D E. |u Research Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vinogradov |D A. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhurakovskii |D I. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Pustovetova |D M. |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ovsyanko |D Ya |u Novosibirsk State Medical University, Ministry of Health of the Russian Federation, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 676-680 |x 0007-4888 |q 158:5<676 |1 2015 |2 158 |o 10517 | ||