caa a22 4500 605539294 CHVBK 20210128100906.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s10396-014-0554-8 doi (NATIONALLICENCE)springer-10.1007/s10396-014-0554-8 Noninvasive evaluation of left ventricular force−frequency relationships by measuring carotid arterial wave intensity during exercise stress [Elektronische Daten] [Midori Tanaka, Motoaki Sugawara, Yasuo Ogasawara, Isao Suminoe, Tadafumi Izumi, Kiyomi Niki, Fumihiko Kajiya] Background and purpose: Estimation of the contractility of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility. We assessed the feasibility of measuring carotid arterial wave intensity and determining force−frequency (contractility−heart rate) relations (FFRs) during exercise totally noninvasively. Methods: We measured carotid arterial wave intensity with a combined color Doppler and echo tracking system in 25 healthy young male volunteers (age 20.8±1.2years) at rest and during exercise. FFRs were constructed by plotting the maximum value of wave intensity (WD1) against heart rate (HR). Results: We first confirmed that HR increased linearly with an increase in work load in each subject (r 2=0.95±0.04). WD1 increased linearly with an increase in HR. The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r 2=0.48−0.94, p<0.0001, respectively). The slope of the WD1-HR relation ranged 0.30−2.20 [m/s3 (beat/min)]. Conclusions: Global LV FFRs can be generated in healthy young volunteers with an entirely noninvasive combination of exercise and wave intensity. These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation. The Japan Society of Ultrasonics in Medicine, 2014 Force−frequency relation nationallicence Echocardiography nationallicence Wave intensity nationallicence Exercise nationallicence Tanaka Midori Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, 670-8524, Himeji, Hyogo, Japan aut Sugawara Motoaki Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, 670-8524, Himeji, Hyogo, Japan aut Ogasawara Yasuo Department of Medical Engineering, Kawasaki University of Medical Welfare, Kurashiki, Japan aut Suminoe Isao Clinical Laboratory, Japanese Red Cross Society, Himeji Hospital, Himeji, Japan aut Izumi Tadafumi Department of Physical Therapy, Health Sciences University of Hokkaido, Ishikari, Japan aut Niki Kiyomi Biomedical Engineering Department, Tokyo City University, Tokyo, Japan aut Kajiya Fumihiko Department of Medical Engineering, Kawasaki University of Medical Welfare, Kurashiki, Japan aut Journal of Medical Ultrasonics Springer Japan 42/1(2015-01-01), 65-70 1346-4523 42:1<65 2015 42 10396 https://doi.org/10.1007/s10396-014-0554-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-014-0554-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tanaka Midori Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, 670-8524, Himeji, Hyogo, Japan aut NATIONALLICENCE 700 1- Sugawara Motoaki Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, 670-8524, Himeji, Hyogo, Japan aut NATIONALLICENCE 700 1- Ogasawara Yasuo Department of Medical Engineering, Kawasaki University of Medical Welfare, Kurashiki, Japan aut NATIONALLICENCE 700 1- Suminoe Isao Clinical Laboratory, Japanese Red Cross Society, Himeji Hospital, Himeji, Japan aut NATIONALLICENCE 700 1- Izumi Tadafumi Department of Physical Therapy, Health Sciences University of Hokkaido, Ishikari, Japan aut NATIONALLICENCE 700 1- Niki Kiyomi Biomedical Engineering Department, Tokyo City University, Tokyo, Japan aut NATIONALLICENCE 700 1- Kajiya Fumihiko Department of Medical Engineering, Kawasaki University of Medical Welfare, Kurashiki, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/1(2015-01-01), 65-70 1346-4523 42:1<65 2015 42 10396