Usefulness of ultrasonographic estimation of preperitoneal and subcutaneous fat thickness in the diagnosis of nonalcoholic fatty liver disease in diabetic patients

Verfasser / Beitragende:
[Kazuto Fukuda, Yasushi Seki, Masahiro Ichihi, Takuya Okada, Ayumu Hirata, Sachiyo Kogita, Yoshiyuki Sawai, Takumi Igura, Mamiko Tsugawa, Yasuharu Imai]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Medical Ultrasonics, 42/3(2015-07-01), 357-363
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10396-015-0615-7  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10396-015-0615-7 
245 0 0 |a Usefulness of ultrasonographic estimation of preperitoneal and subcutaneous fat thickness in the diagnosis of nonalcoholic fatty liver disease in diabetic patients  |h [Elektronische Daten]  |c [Kazuto Fukuda, Yasushi Seki, Masahiro Ichihi, Takuya Okada, Ayumu Hirata, Sachiyo Kogita, Yoshiyuki Sawai, Takumi Igura, Mamiko Tsugawa, Yasuharu Imai] 
520 3 |a Purpose: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have been regarded as the hepatic manifestation of metabolic syndrome. Abdominal wall fat index (AFI), defined as the ratio of preperitoneal and subcutaneous fat thickness in the abdomen estimated by ultrasonography (US), has been shown to be useful in screening for disorders related to metabolic syndrome. We investigated the relation between AFI and NAFLD/NASH in diabetic patients. Methods: The degree of fat accumulation in the liver and the thickness of preperitoneal and subcutaneous fat were determined by US in 340 diabetic patients. An NAFLD fibrosis score (NAFLD-FS) was used to assess the advancement of hepatic fibrosis in NAFLD patients. Results: Of all 340 subjects, 209 (61%) were diagnosed with NAFLD by US. AFI of NAFLD subjects was significantly higher than that of non-NAFLD subjects. Of the 209 subjects with NAFLD, 31 (15%) were shown to have advanced NASH fibrosis according to NAFLD-FS. Multivariate analysis identified AFI as a significant predictor of advanced fibrosis. Conclusion: AFI easily obtained by US was significantly related to the presence of NAFLD and/or advanced hepatic fibrosis in diabetic patients. 
540 |a The Japan Society of Ultrasonics in Medicine, 2015 
690 7 |a NAFLD  |2 nationallicence 
690 7 |a NASH  |2 nationallicence 
690 7 |a Visceral fat  |2 nationallicence 
690 7 |a Diabetes mellitus  |2 nationallicence 
690 7 |a Ultrasonography  |2 nationallicence 
690 7 |a NAFLD : Nonalcoholic fatty liver disease  |2 nationallicence 
690 7 |a NASH : Nonalcoholic steatohepatitis  |2 nationallicence 
690 7 |a HCC : Hepatocellular carcinoma  |2 nationallicence 
690 7 |a AFI : Abdominal wall fat index  |2 nationallicence 
690 7 |a US : Ultrasonography  |2 nationallicence 
690 7 |a NAFLD-FS : NFLD fibrosis score  |2 nationallicence 
690 7 |a DM : Diabetes mellitus  |2 nationallicence 
690 7 |a CT : Computed tomography  |2 nationallicence 
690 7 |a MRI : Magnetic resonance imaging  |2 nationallicence 
690 7 |a BMI : Body mass index  |2 nationallicence 
700 1 |a Fukuda  |D Kazuto  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
700 1 |a Seki  |D Yasushi  |u Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
700 1 |a Ichihi  |D Masahiro  |u Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
700 1 |a Okada  |D Takuya  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
700 1 |a Hirata  |D Ayumu  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
700 1 |a Kogita  |D Sachiyo  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
700 1 |a Sawai  |D Yoshiyuki  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
700 1 |a Igura  |D Takumi  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
700 1 |a Tsugawa  |D Mamiko  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
700 1 |a Imai  |D Yasuharu  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
773 0 |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/3(2015-07-01), 357-363  |x 1346-4523  |q 42:3<357  |1 2015  |2 42  |o 10396 
856 4 0 |u https://doi.org/10.1007/s10396-015-0615-7  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10396-015-0615-7  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fukuda  |D Kazuto  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Seki  |D Yasushi  |u Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ichihi  |D Masahiro  |u Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Okada  |D Takuya  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hirata  |D Ayumu  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kogita  |D Sachiyo  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sawai  |D Yoshiyuki  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Igura  |D Takumi  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tsugawa  |D Mamiko  |u Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Imai  |D Yasuharu  |u Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/3(2015-07-01), 357-363  |x 1346-4523  |q 42:3<357  |1 2015  |2 42  |o 10396