caa a22 4500 605539502 CHVBK 20210128100907.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10396-015-0615-7 doi (NATIONALLICENCE)springer-10.1007/s10396-015-0615-7 Usefulness of ultrasonographic estimation of preperitoneal and subcutaneous fat thickness in the diagnosis of nonalcoholic fatty liver disease in diabetic patients [Elektronische Daten] [Kazuto Fukuda, Yasushi Seki, Masahiro Ichihi, Takuya Okada, Ayumu Hirata, Sachiyo Kogita, Yoshiyuki Sawai, Takumi Igura, Mamiko Tsugawa, Yasuharu Imai] Purpose: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have been regarded as the hepatic manifestation of metabolic syndrome. Abdominal wall fat index (AFI), defined as the ratio of preperitoneal and subcutaneous fat thickness in the abdomen estimated by ultrasonography (US), has been shown to be useful in screening for disorders related to metabolic syndrome. We investigated the relation between AFI and NAFLD/NASH in diabetic patients. Methods: The degree of fat accumulation in the liver and the thickness of preperitoneal and subcutaneous fat were determined by US in 340 diabetic patients. An NAFLD fibrosis score (NAFLD-FS) was used to assess the advancement of hepatic fibrosis in NAFLD patients. Results: Of all 340 subjects, 209 (61%) were diagnosed with NAFLD by US. AFI of NAFLD subjects was significantly higher than that of non-NAFLD subjects. Of the 209 subjects with NAFLD, 31 (15%) were shown to have advanced NASH fibrosis according to NAFLD-FS. Multivariate analysis identified AFI as a significant predictor of advanced fibrosis. Conclusion: AFI easily obtained by US was significantly related to the presence of NAFLD and/or advanced hepatic fibrosis in diabetic patients. The Japan Society of Ultrasonics in Medicine, 2015 NAFLD nationallicence NASH nationallicence Visceral fat nationallicence Diabetes mellitus nationallicence Ultrasonography nationallicence NAFLD : Nonalcoholic fatty liver disease nationallicence NASH : Nonalcoholic steatohepatitis nationallicence HCC : Hepatocellular carcinoma nationallicence AFI : Abdominal wall fat index nationallicence US : Ultrasonography nationallicence NAFLD-FS : NFLD fibrosis score nationallicence DM : Diabetes mellitus nationallicence CT : Computed tomography nationallicence MRI : Magnetic resonance imaging nationallicence BMI : Body mass index nationallicence Fukuda Kazuto Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut Seki Yasushi Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan aut Ichihi Masahiro Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan aut Okada Takuya Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut Hirata Ayumu Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut Kogita Sachiyo Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut Sawai Yoshiyuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut Igura Takumi Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut Tsugawa Mamiko Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut Imai Yasuharu Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut Journal of Medical Ultrasonics Springer Japan 42/3(2015-07-01), 357-363 1346-4523 42:3<357 2015 42 10396 https://doi.org/10.1007/s10396-015-0615-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-015-0615-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fukuda Kazuto Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Seki Yasushi Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan aut NATIONALLICENCE 700 1- Ichihi Masahiro Department of Ultrasonography, Ikeda Municipal Hospital, Ikeda, Japan aut NATIONALLICENCE 700 1- Okada Takuya Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut NATIONALLICENCE 700 1- Hirata Ayumu Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut NATIONALLICENCE 700 1- Kogita Sachiyo Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Sawai Yoshiyuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Igura Takumi Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Tsugawa Mamiko Department of Endocrinology and Metabolism, Ikeda Municipal Hospital, Ikeda, Japan aut NATIONALLICENCE 700 1- Imai Yasuharu Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18 Jonan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/3(2015-07-01), 357-363 1346-4523 42:3<357 2015 42 10396