caa a22 4500 605539642 CHVBK 20210128100907.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s10396-014-0607-z doi (NATIONALLICENCE)springer-10.1007/s10396-014-0607-z Spontaneous regression of breast angiosarcoma after conservative treatment with radiotherapy: a case report and review of the literature [Elektronische Daten] [Yuko Tanaka, Atsushi Uchida, Takeshi Umemoto, Isamu Morishima, Kazunori Kikuchi, Eriko Tohno, Ei Ueno] Angiosarcoma of the breast is a rare disease, and approximately 1% of all affected patients are treated with breast-conserving therapy (BCT) and radiotherapy (RT) for primary breast cancer. The prognosis for this tumor is quite dismal, with high rates of recurrence and poor overall survival. This report presents the case of a 73-year-old female who underwent BCT followed by RT for left breast carcinoma 18years previously. The patient visited the hospital with a complaint of a new mass in the left breast. The lesion initially decreased in size; however, it subsequently began to rapidly enlarge. A core needle biopsy of the mass was performed under ultrasonography, with a diagnosis of a spindle cell sarcoma, most conceivably an angiosarcoma, originating from the left breast, suspected to be induced by RT. The tumor was resected with the surrounding skin, and immunohistochemically diagnosed as angiosarcoma of the left breast, without evidence of breast cancer in any lesion, suggesting that RT induced the tumor formation. We herein report this rare case and the ultrasound imaging findings. The Japan Society of Ultrasonics in Medicine, 2014 Angiosarcoma nationallicence Breast cancer nationallicence Radiation-induced malignancy nationallicence Tumor regression nationallicence BCT : Breast-conserving therapy nationallicence RT : Radiotherapy nationallicence CT : Computed tomography nationallicence MRI : Magnetic resonance imaging nationallicence Tanaka Yuko Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Uchida Atsushi Department of Pathology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Umemoto Takeshi Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Morishima Isamu Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Kikuchi Kazunori Department of Pathology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Tohno Eriko Total Health Evaluation Center Tsukuba, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Ueno Ei Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut Journal of Medical Ultrasonics Springer Japan 42/3(2015-07-01), 427-432 1346-4523 42:3<427 2015 42 10396 https://doi.org/10.1007/s10396-014-0607-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-014-0607-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tanaka Yuko Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Uchida Atsushi Department of Pathology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Umemoto Takeshi Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Morishima Isamu Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Kikuchi Kazunori Department of Pathology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Tohno Eriko Total Health Evaluation Center Tsukuba, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Ueno Ei Department of Senology, Tsukuba Medical Center Hospital, 1-3-1 Amakubo, 305-8558, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/3(2015-07-01), 427-432 1346-4523 42:3<427 2015 42 10396