caa a22 4500 605539669 CHVBK 20210128100907.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10396-015-0628-2 doi (NATIONALLICENCE)springer-10.1007/s10396-015-0628-2 The role of transvaginal power Doppler ultrasound in the differential diagnosis of benign intrauterine focal lesions [Elektronische Daten] [Ebru Cogendez, Meryem Eken, Nuray Bakal, Ismet Gun, Ecmel Kaygusuz, Ates Karateke] Purpose: The purpose of this prospective study was to assess the role of power Doppler imaging in the differential diagnosis of benign intrauterine focal lesions such as endometrial polyps and submucous myomas using the characteristics of power Doppler flow mapping. Methods: A total of 480 premenopausal patients with abnormal uterine bleeding were evaluated by transvaginal ultrasonography (TVS) searching for intrauterine pathology. Sixty-four patients with a suspicious focal endometrial lesion received saline infusion sonography (SIS) after TVS. Fifty-eight patients with focal endometrial lesions underwent power Doppler ultrasound (PDUS). Three different vascular flow patterns were defined: Single vessel pattern, multiple vessel pattern, and circular flow pattern. Finally, hysteroscopic resection was performed in all cases, and Doppler flow characteristics were then compared with the final histopathological findings. Results: Histopathological results were as follows: endometrial polyp: 40 (69%), submucous myoma: 18 (31%). Of the cases with endometrial polyps, 80% demonstrated a single vessel pattern, 7.5% a multiple vessel pattern, and 0% a circular pattern. Vascularization was not observed in 12.5% of patients with polyps. Of the cases with submucousal myomas, 72.2% demonstrated a circular flow pattern, 27.8% a multiple vessel pattern, and none of them showed a single vessel pattern. The sensitivity, specificity, and positive and negative predictive values of the single vessel pattern in diagnosing endometrial polyps were 80, 100, 100, and 69.2%, respectively; and for the circular pattern in diagnosing submucous myoma, these were 72.2, 100, 100, and 88.9%, respectively. Conclusion: Power Doppler blood flow mapping is a useful, practical, and noninvasive diagnostic method for the differential diagnosis of benign intrauterine focal lesions. Especially in cases of recurrent abnormal uterine bleeding, recurrent abortion, and infertility, PDUS can be preferred as a first-line diagnostic method. The Japan Society of Ultrasonics in Medicine, 2015 Power Doppler ultrasound nationallicence Endometrial polyp nationallicence Submucous myoma nationallicence Cogendez Ebru Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut Eken Meryem Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut Bakal Nuray Radiology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut Gun Ismet Gynecology Department, GATA Haydarpasa Training Hospital, Istanbul, Turkey aut Kaygusuz Ecmel Pathology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut Karateke Ates Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 533-540 1346-4523 42:4<533 2015 42 10396 https://doi.org/10.1007/s10396-015-0628-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-015-0628-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cogendez Ebru Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Eken Meryem Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Bakal Nuray Radiology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Gun Ismet Gynecology Department, GATA Haydarpasa Training Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Kaygusuz Ecmel Pathology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Karateke Ates Gynecology Department, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 533-540 1346-4523 42:4<533 2015 42 10396