Modeling the thermo-acoustic effects of thermal-dependent speed of sound and acoustic absorption of biological tissues during focused ultrasound hyperthermia

Verfasser / Beitragende:
[S. López-Haro, M. Gutiérrez, A. Vera, L. Leija]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Medical Ultrasonics, 42/4(2015-10-01), 489-498
Format:
Artikel (online)
ID: 605539774
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024 7 0 |a 10.1007/s10396-015-0643-3  |2 doi 
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245 0 0 |a Modeling the thermo-acoustic effects of thermal-dependent speed of sound and acoustic absorption of biological tissues during focused ultrasound hyperthermia  |h [Elektronische Daten]  |c [S. López-Haro, M. Gutiérrez, A. Vera, L. Leija] 
520 3 |a Purpose: To evaluate the effects of thermal dependence of speed of sound (SOS) and acoustic absorption of biological tissues during noninvasive focused ultrasound (US) hyperthermia therapy. Methods: A finite element (FE) model was used to simulate hyperthermia therapy in the liver by noninvasive focused US. The model consisted of an ultrasonic focused transducer radiating a four-layer biological medium composed of skin, fat, muscle, and liver. The acoustic field and temperature distribution along the layers were obtained after 15s of hyperthermia therapy using the bio-heat equation. The model solution was found with and without the thermal dependence of SOS and acoustic absorption of biological tissues. Results: The inclusion of the thermal dependence of the SOS generated an increment of 0.4mm in the longitudinal focus axis of the acoustic field. Moreover, results indicate an increment of the hyperthermia area (zone with temperature above 43°C), and a maximum temperature difference of almost 3.5°C when the thermal dependence of absorption was taken into account. Conclusion: The increment of the achieved temperatures at the treatment zone indicated that the effects produced by the thermal dependence of SOS and absorption must be accounted for when planning hyperthermia treatment in order to avoid overheating undesired regions. 
540 |a The Japan Society of Ultrasonics in Medicine, 2015 
690 7 |a Absorption  |2 nationallicence 
690 7 |a Speed of sound  |2 nationallicence 
690 7 |a Temperature dependence  |2 nationallicence 
690 7 |a Finite element  |2 nationallicence 
690 7 |a Hyperthermia  |2 nationallicence 
690 7 |a Ultrasound  |2 nationallicence 
700 1 |a López-Haro  |D S.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
700 1 |a Gutiérrez  |D M.  |u Instituto Nacional de Rehabilitación, CONACyT, Subdirección de Investigación Tecnológica, Calz. México Xochimilco No. 289, Col. Arenal de Guadalupe, Del. Xochimilco, 14389, Mexico City, Mexico  |4 aut 
700 1 |a Vera  |D A.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
700 1 |a Leija  |D L.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
773 0 |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/4(2015-10-01), 489-498  |x 1346-4523  |q 42:4<489  |1 2015  |2 42  |o 10396 
856 4 0 |u https://doi.org/10.1007/s10396-015-0643-3  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a López-Haro  |D S.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Gutiérrez  |D M.  |u Instituto Nacional de Rehabilitación, CONACyT, Subdirección de Investigación Tecnológica, Calz. México Xochimilco No. 289, Col. Arenal de Guadalupe, Del. Xochimilco, 14389, Mexico City, Mexico  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Vera  |D A.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Leija  |D L.  |u Electrical Engineering Department, Bioelectronics Section, Centro de Investigación y de Estudios Avanzados del IPN, Cinvestav-IPN, Av. IPN 2508, Col. San Pedro Zacatenco, Del. Gustavo A. Madero, 07360, Mexico City, Mexico  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/4(2015-10-01), 489-498  |x 1346-4523  |q 42:4<489  |1 2015  |2 42  |o 10396