Effect of obstructive jaundice on hepatic hemodynamics: use of Sonazoid-enhanced ultrasonography in a prospective study of the blood flow balance between the hepatic portal vein and hepatic artery

Verfasser / Beitragende:
[Noritaka Wakui, Yuki Takeda, Shuta Nishinakagawa, Nobuo Ueki, Takafumi Otsuka, Nobuyuki Oba, Hiroshi Hashimoto, Naohisa Kamiyama, Yasukiyo Sumino, Tatsuya Kojima]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Medical Ultrasonics, 42/4(2015-10-01), 513-520
Format:
Artikel (online)
ID: 605539804
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024 7 0 |a 10.1007/s10396-015-0629-1  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10396-015-0629-1 
245 0 0 |a Effect of obstructive jaundice on hepatic hemodynamics: use of Sonazoid-enhanced ultrasonography in a prospective study of the blood flow balance between the hepatic portal vein and hepatic artery  |h [Elektronische Daten]  |c [Noritaka Wakui, Yuki Takeda, Shuta Nishinakagawa, Nobuo Ueki, Takafumi Otsuka, Nobuyuki Oba, Hiroshi Hashimoto, Naohisa Kamiyama, Yasukiyo Sumino, Tatsuya Kojima] 
520 3 |a Purpose: To prospectively clarify the effects of obstructive jaundice (OJ) on hepatic hemodynamics using contrast-enhanced ultrasonography (US). Methods: Subjects comprised 14 patients admitted to our hospital for OJ between April 2013 and March 2014. Contrast-enhanced US was performed using the LOGIQ E9 ultrasound device during the jaundice phase, before biliary drainage, and again after improvement of jaundice. After injecting the Sonazoid contrast agent, contrast dynamics were recorded in the right kidney and liver segments 5 or 6. Prototype software was used to calculate mean arrival time (AT) of the contrast agent in the liver parenchyma. Statistical analysis was performed to compare the mean AT in the jaundice and improved jaundice phases. Results: We were unable to follow up three of the 14 patients after biliary drainage; thus, we included 11 patients for further analysis. The mean AT of the contrast agent was 2.0±1.8 and 6.1±2.3s in the jaundice and improved jaundice phases, respectively, showing significantly shorter AT in the jaundice phase (p=0.0033). Conclusion: Our findings indicate that OJ may influence the blood flow balance between the hepatic portal vein and hepatic artery. 
540 |a The Japan Society of Ultrasonics in Medicine, 2015 
690 7 |a Obstructive jaundice  |2 nationallicence 
690 7 |a Arrival time parametric imaging  |2 nationallicence 
690 7 |a Sonazoid  |2 nationallicence 
690 7 |a Contrast-enhanced ultrasonography  |2 nationallicence 
700 1 |a Wakui  |D Noritaka  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Takeda  |D Yuki  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Nishinakagawa  |D Shuta  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Ueki  |D Nobuo  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Otsuka  |D Takafumi  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Oba  |D Nobuyuki  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
700 1 |a Hashimoto  |D Hiroshi  |u Ultrasound General Imaging, GE Healthcare, Tokyo, Japan  |4 aut 
700 1 |a Kamiyama  |D Naohisa  |u Ultrasound General Imaging, GE Healthcare, Tokyo, Japan  |4 aut 
700 1 |a Sumino  |D Yasukiyo  |u Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, 6-11-1 Omori-nishi, Ota, 143-8541, Tokyo, Japan  |4 aut 
700 1 |a Kojima  |D Tatsuya  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
773 0 |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/4(2015-10-01), 513-520  |x 1346-4523  |q 42:4<513  |1 2015  |2 42  |o 10396 
856 4 0 |u https://doi.org/10.1007/s10396-015-0629-1  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10396-015-0629-1  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wakui  |D Noritaka  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takeda  |D Yuki  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nishinakagawa  |D Shuta  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ueki  |D Nobuo  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Otsuka  |D Takafumi  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Oba  |D Nobuyuki  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hashimoto  |D Hiroshi  |u Ultrasound General Imaging, GE Healthcare, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kamiyama  |D Naohisa  |u Ultrasound General Imaging, GE Healthcare, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sumino  |D Yasukiyo  |u Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, 6-11-1 Omori-nishi, Ota, 143-8541, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kojima  |D Tatsuya  |u Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Medical Ultrasonics  |d Springer Japan  |g 42/4(2015-10-01), 513-520  |x 1346-4523  |q 42:4<513  |1 2015  |2 42  |o 10396