caa a22 4500 605539804 CHVBK 20210128100908.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10396-015-0629-1 doi (NATIONALLICENCE)springer-10.1007/s10396-015-0629-1 Effect of obstructive jaundice on hepatic hemodynamics: use of Sonazoid-enhanced ultrasonography in a prospective study of the blood flow balance between the hepatic portal vein and hepatic artery [Elektronische Daten] [Noritaka Wakui, Yuki Takeda, Shuta Nishinakagawa, Nobuo Ueki, Takafumi Otsuka, Nobuyuki Oba, Hiroshi Hashimoto, Naohisa Kamiyama, Yasukiyo Sumino, Tatsuya Kojima] Purpose: To prospectively clarify the effects of obstructive jaundice (OJ) on hepatic hemodynamics using contrast-enhanced ultrasonography (US). Methods: Subjects comprised 14 patients admitted to our hospital for OJ between April 2013 and March 2014. Contrast-enhanced US was performed using the LOGIQ E9 ultrasound device during the jaundice phase, before biliary drainage, and again after improvement of jaundice. After injecting the Sonazoid contrast agent, contrast dynamics were recorded in the right kidney and liver segments 5 or 6. Prototype software was used to calculate mean arrival time (AT) of the contrast agent in the liver parenchyma. Statistical analysis was performed to compare the mean AT in the jaundice and improved jaundice phases. Results: We were unable to follow up three of the 14 patients after biliary drainage; thus, we included 11 patients for further analysis. The mean AT of the contrast agent was 2.0±1.8 and 6.1±2.3s in the jaundice and improved jaundice phases, respectively, showing significantly shorter AT in the jaundice phase (p=0.0033). Conclusion: Our findings indicate that OJ may influence the blood flow balance between the hepatic portal vein and hepatic artery. The Japan Society of Ultrasonics in Medicine, 2015 Obstructive jaundice nationallicence Arrival time parametric imaging nationallicence Sonazoid nationallicence Contrast-enhanced ultrasonography nationallicence Wakui Noritaka Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Takeda Yuki Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Nishinakagawa Shuta Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Ueki Nobuo Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Otsuka Takafumi Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Oba Nobuyuki Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Hashimoto Hiroshi Ultrasound General Imaging, GE Healthcare, Tokyo, Japan aut Kamiyama Naohisa Ultrasound General Imaging, GE Healthcare, Tokyo, Japan aut Sumino Yasukiyo Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, 6-11-1 Omori-nishi, Ota, 143-8541, Tokyo, Japan aut Kojima Tatsuya Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 513-520 1346-4523 42:4<513 2015 42 10396 https://doi.org/10.1007/s10396-015-0629-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-015-0629-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wakui Noritaka Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Takeda Yuki Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Nishinakagawa Shuta Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Ueki Nobuo Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Otsuka Takafumi Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Oba Nobuyuki Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Hashimoto Hiroshi Ultrasound General Imaging, GE Healthcare, Tokyo, Japan aut NATIONALLICENCE 700 1- Kamiyama Naohisa Ultrasound General Imaging, GE Healthcare, Tokyo, Japan aut NATIONALLICENCE 700 1- Sumino Yasukiyo Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, 6-11-1 Omori-nishi, Ota, 143-8541, Tokyo, Japan aut NATIONALLICENCE 700 1- Kojima Tatsuya Department of Internal Gastroenterology and Hepatology, Tokyo Rosai Hospital, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 513-520 1346-4523 42:4<513 2015 42 10396