caa a22 4500 605539898 CHVBK 20210128100909.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10396-015-0633-5 doi (NATIONALLICENCE)springer-10.1007/s10396-015-0633-5 A preliminary prospective study to compare the diagnostic performance of assist strain ratio versus manual strain ratio [Elektronische Daten] [Ei Ueno, Eriko Tohno, Isamu Morishima, Takeshi Umemoto, Koji Waki] Objectives: The objectives of this study were to demonstrate the non-inferiority of assist strain ratio (ASR)—a newly developed application tool—to manual strain ratio (MSR)—a currently available standard diagnostic tool—and to calculate the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MSR and ASR. Methods: Ninety-eight mass lesions in the mammary gland (30 malignant and 68 benign) were included in the study. Skilled physicians performed the elastography scanning by applying minimal vibration. MSRs were obtained and compared with ASRs calculated from the same elastography image to test the correlation between the two groups of data. Results: Diagnostic performance of MSR at a cut-off of 5.0 showed a sensitivity of 84.4 %, a specificity of 80.4 %, an accuracy of 81.6 %, a PPV of 65.5 %, and an NPV of 92.1 %. Diagnostic performance of ASR at a cut-off of 5.0 showed a sensitivity of 74.4 %, a specificity of 84.3 %, an accuracy of 81.3 %, a PPV of 67.7 %, and an NPV of 88.2 %. The areas under the curve (AUCs) for MSR and ASR were found to be 0.885 and 0.875, respectively. Conclusion: ASR demonstrated excellent diagnostic potential and was highly correlated with MSR performed by skilled physicians (r=0.69, p<0.05). The Japan Society of Ultrasonics in Medicine, 2015 Elastography nationallicence Strain ratio nationallicence FLR nationallicence Assist strain ratio nationallicence Breast cancer nationallicence Ueno Ei Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut Tohno Eriko Total Health Evaluation Center Tsukuba, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut Morishima Isamu Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut Umemoto Takeshi Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut Waki Koji Medical Systems Engineering Division 2, Hitachi Aloka Medical, Ltd., Kokubunji, Tokyo, Japan aut Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 521-531 1346-4523 42:4<521 2015 42 10396 https://doi.org/10.1007/s10396-015-0633-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-015-0633-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ueno Ei Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Tohno Eriko Total Health Evaluation Center Tsukuba, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Morishima Isamu Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Umemoto Takeshi Department of Senology, Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Waki Koji Medical Systems Engineering Division 2, Hitachi Aloka Medical, Ltd., Kokubunji, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/4(2015-10-01), 521-531 1346-4523 42:4<521 2015 42 10396