caa a22 4500 605540012 CHVBK 20210128100909.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10396-014-0580-6 doi (NATIONALLICENCE)springer-10.1007/s10396-014-0580-6 A rare case of fungal endocarditis caused by Candida glabrata after completion of antibiotic therapy for Streptococcus endocarditis [Elektronische Daten] [Toshimitsu Tsugu, Mitsushige Murata, Shiro Iwanaga, Yohei Kitamura, Soushin Inoue, Keiichi Fukuda] We present the rare case of a 76-year-old female with infective endocarditis (IE) caused by Candida glabrata. Immediately before developing the present infection, she developed IE with vegetation on the mitral annular calcification, which was caused by Streptococcus mitis and successfully treated with penicillin-G and gentamicin. However, her fever recurred, and she developed disseminated intravascular coagulation. Blood culture revealed C. glabrata, and echocardiography revealed new vegetation on the mitral valve. After 4weeks of treatment with micafungin, prosthetic valve replacement was performed, followed by additional administration of micafungin for 4weeks (total of 8weeks). No relapse at 9months after surgery has been observed. C. glabrata endocarditis is extremely rare and difficult to manage. Our case and review of past reported cases suggest that early diagnosis and initiation of treatment contribute to good prognosis of C. glabrata endocarditis. The Japan Society of Ultrasonics in Medicine, 2014 Echocardiography nationallicence Fungal endocarditis nationallicence Mitral valve replacement nationallicence Candida glabrata nationallicence Micafungin nationallicence Tsugu Toshimitsu Department of Cardiology, School of Medicine, Keio University, Tokyo, Japan aut Murata Mitsushige Department of Laboratory Medicine, School of Medicine, Keio University, Tokyo, Japan aut Iwanaga Shiro Department of Cardiology, Saitama International Medical Center, Saitama, Japan aut Kitamura Yohei Department of Neurosurgery, Hino Municipal Hospital, Tokyo, Japan aut Inoue Soushin Department of Cardiology, Hino Municipal Hospital, 4-3-1, Tamadaira, 191-0062, Hino, Tokyo, Japan aut Fukuda Keiichi Department of Cardiology, School of Medicine, Keio University, Tokyo, Japan aut Journal of Medical Ultrasonics Springer Japan 42/2(2015-04-01), 243-246 1346-4523 42:2<243 2015 42 10396 https://doi.org/10.1007/s10396-014-0580-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10396-014-0580-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tsugu Toshimitsu Department of Cardiology, School of Medicine, Keio University, Tokyo, Japan aut NATIONALLICENCE 700 1- Murata Mitsushige Department of Laboratory Medicine, School of Medicine, Keio University, Tokyo, Japan aut NATIONALLICENCE 700 1- Iwanaga Shiro Department of Cardiology, Saitama International Medical Center, Saitama, Japan aut NATIONALLICENCE 700 1- Kitamura Yohei Department of Neurosurgery, Hino Municipal Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Inoue Soushin Department of Cardiology, Hino Municipal Hospital, 4-3-1, Tamadaira, 191-0062, Hino, Tokyo, Japan aut NATIONALLICENCE 700 1- Fukuda Keiichi Department of Cardiology, School of Medicine, Keio University, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Medical Ultrasonics Springer Japan 42/2(2015-04-01), 243-246 1346-4523 42:2<243 2015 42 10396