Cadherins in tissue architecture and disease
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| 024 | 7 | 0 | |a 10.1007/s00109-014-1231-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00109-014-1231-5 | ||
| 100 | 1 | |a Vestweber |D Dietmar |u Max Planck Institute for Molecular Biomedicine, Röntgenstr. 20, 48149, Münster, Germany |4 aut | |
| 245 | 1 | 0 | |a Cadherins in tissue architecture and disease |h [Elektronische Daten] |c [Dietmar Vestweber] |
| 520 | 3 | |a Cadherins are homophilic cell adhesion molecules that determine tissue architecture and control cell contact formation and dissociation in development and tissue homeostasis of all metazoans. These adhesion molecules mediate homophilic interactions between cells and are linked inside the cell via a complex set of cytosolic factors to the actin cytoskeleton. These interactions are key to the plasticity of intercellular junctions and to the various signaling functions of the cadherins. This forms the basis for cadherin-driven cell behavior, cell differentiation, and regeneration of tissue structures. Consequently, mutations in cadherins are the cause of various human pathologies, with cancer representing one of the most prominent examples. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Cell adhesion |2 nationallicence | |
| 690 | 7 | |a Cadherins |2 nationallicence | |
| 690 | 7 | |a Catenins |2 nationallicence | |
| 690 | 7 | |a Junctions |2 nationallicence | |
| 690 | 7 | |a Mechanotransduction |2 nationallicence | |
| 690 | 7 | |a Cancer |2 nationallicence | |
| 773 | 0 | |t Journal of Molecular Medicine |d Springer Berlin Heidelberg |g 93/1(2015-01-01), 5-11 |x 0946-2716 |q 93:1<5 |1 2015 |2 93 |o 109 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00109-014-1231-5 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00109-014-1231-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 100 |E 1- |a Vestweber |D Dietmar |u Max Planck Institute for Molecular Biomedicine, Röntgenstr. 20, 48149, Münster, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Molecular Medicine |d Springer Berlin Heidelberg |g 93/1(2015-01-01), 5-11 |x 0946-2716 |q 93:1<5 |1 2015 |2 93 |o 109 | ||