Nlrp1 inflammasome is downregulated in trauma patients

Verfasser / Beitragende:
[B. Relja, J. Horstmann, K. Kontradowitz, K. Jurida, A. Schaible, C. Neunaber, E. Oppermann, I. Marzi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Molecular Medicine, 93/12(2015-12-01), 1391-1400
Format:
Artikel (online)
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245 0 0 |a Nlrp1 inflammasome is downregulated in trauma patients  |h [Elektronische Daten]  |c [B. Relja, J. Horstmann, K. Kontradowitz, K. Jurida, A. Schaible, C. Neunaber, E. Oppermann, I. Marzi] 
540 |a Springer-Verlag Berlin Heidelberg, 2015 
690 7 |a Immune suppression  |2 nationallicence 
690 7 |a Monocytes  |2 nationallicence 
690 7 |a Inflammasome  |2 nationallicence 
690 7 |a Nlrp  |2 nationallicence 
690 7 |a AIS : Abbreviated injury scale  |2 nationallicence 
690 7 |a ASC : Apoptosis-associated speck-like protein containing CARD  |2 nationallicence 
690 7 |a BSA : Bovine serum albumin  |2 nationallicence 
690 7 |a CARD : Caspase activation and recruitment domain  |2 nationallicence 
690 7 |a CASP1 : Caspase-1  |2 nationallicence 
690 7 |a CD : Cluster of differentiation  |2 nationallicence 
690 7 |a Ctrl : Control  |2 nationallicence 
690 7 |a DAMP : Damage-associated molecular pattern  |2 nationallicence 
690 7 |a ED : Emergency department  |2 nationallicence 
690 7 |a ELISA : Enzyme-linked immunosorbent assay  |2 nationallicence 
690 7 |a EDTA : Ethylenediaminetetraacetic acid  |2 nationallicence 
690 7 |a GAPDH : Glyceraldehyde 3-phosphate dehydrogenase  |2 nationallicence 
690 7 |a HV : Healthy volunteers  |2 nationallicence 
690 7 |a ICU : Intensive care unit  |2 nationallicence 
690 7 |a IL : Interleukin  |2 nationallicence 
690 7 |a ISS : Injury severity score  |2 nationallicence 
690 7 |a LRR : Leucin-rich repeats  |2 nationallicence 
690 7 |a LPS : Lipopolysaccharide  |2 nationallicence 
690 7 |a mRNA : Messenger ribonucleic acid  |2 nationallicence 
690 7 |a NLR : NOD-like receptor  |2 nationallicence 
690 7 |a Nlrp : NLR sensor molecule containing pyrin domaine  |2 nationallicence 
690 7 |a PBS : Phosphate-buffered saline  |2 nationallicence 
690 7 |a PAMPs : Pathogen-associated molecular pattern  |2 nationallicence 
690 7 |a PC : Plasmid ctrl  |2 nationallicence 
690 7 |a PRR : Pattern recognition receptors  |2 nationallicence 
690 7 |a PYCARD : Gene encoding for ASC  |2 nationallicence 
690 7 |a TP : Trauma patients  |2 nationallicence 
700 1 |a Relja  |D B.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Horstmann  |D J.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Kontradowitz  |D K.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Jurida  |D K.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Schaible  |D A.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Neunaber  |D C.  |u Trauma Department, Hannover Medical School, Hannover, Germany  |4 aut 
700 1 |a Oppermann  |D E.  |u Department of General and Visceral Surgery, Goethe University, Frankfurt, Germany  |4 aut 
700 1 |a Marzi  |D I.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
773 0 |t Journal of Molecular Medicine  |d Springer Berlin Heidelberg  |g 93/12(2015-12-01), 1391-1400  |x 0946-2716  |q 93:12<1391  |1 2015  |2 93  |o 109 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Relja  |D B.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Horstmann  |D J.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kontradowitz  |D K.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Jurida  |D K.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Schaible  |D A.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Neunaber  |D C.  |u Trauma Department, Hannover Medical School, Hannover, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Oppermann  |D E.  |u Department of General and Visceral Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Marzi  |D I.  |u Department of Trauma, Hand and Reconstructive Surgery, Goethe University, Frankfurt, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Molecular Medicine  |d Springer Berlin Heidelberg  |g 93/12(2015-12-01), 1391-1400  |x 0946-2716  |q 93:12<1391  |1 2015  |2 93  |o 109