New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases

Verfasser / Beitragende:
[Marie-Hélène Disatnik, Sunhee Hwang, Julio Ferreira, Daria Mochly-Rosen]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Molecular Medicine, 93/3(2015-03-01), 279-287
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00109-015-1256-4  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00109-015-1256-4 
245 0 0 |a New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases  |h [Elektronische Daten]  |c [Marie-Hélène Disatnik, Sunhee Hwang, Julio Ferreira, Daria Mochly-Rosen] 
520 3 |a The processes that control the number and shape of the mitochondria (mitochondrial dynamics) and the removal of damaged mitochondria (mitophagy) have been the subject of intense research. Recent work indicates that these processes may contribute to the pathology associated with cardiac diseases. This review describes some of the key proteins that regulate these processes and their potential as therapeutic targets for cardiac diseases. 
540 |a The Author(s), 2015 
690 7 |a Cardiac disease  |2 nationallicence 
690 7 |a Mitochondria  |2 nationallicence 
690 7 |a Mitophagy  |2 nationallicence 
690 7 |a Autophagy  |2 nationallicence 
690 7 |a Fission  |2 nationallicence 
690 7 |a Fusion  |2 nationallicence 
690 7 |a Mitochondrial dynamics  |2 nationallicence 
690 7 |a Heart  |2 nationallicence 
700 1 |a Disatnik  |D Marie-Hélène  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
700 1 |a Hwang  |D Sunhee  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
700 1 |a Ferreira  |D Julio  |u Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, 05508-000, São Paulo, Brazil  |4 aut 
700 1 |a Mochly-Rosen  |D Daria  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
773 0 |t Journal of Molecular Medicine  |d Springer Berlin Heidelberg  |g 93/3(2015-03-01), 279-287  |x 0946-2716  |q 93:3<279  |1 2015  |2 93  |o 109 
856 4 0 |u https://doi.org/10.1007/s00109-015-1256-4  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00109-015-1256-4  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Disatnik  |D Marie-Hélène  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hwang  |D Sunhee  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ferreira  |D Julio  |u Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, 05508-000, São Paulo, Brazil  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mochly-Rosen  |D Daria  |u Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Molecular Medicine  |d Springer Berlin Heidelberg  |g 93/3(2015-03-01), 279-287  |x 0946-2716  |q 93:3<279  |1 2015  |2 93  |o 109