caa a22 4500 605543453 CHVBK 20210128100926.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00109-015-1256-4 doi (NATIONALLICENCE)springer-10.1007/s00109-015-1256-4 New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases [Elektronische Daten] [Marie-Hélène Disatnik, Sunhee Hwang, Julio Ferreira, Daria Mochly-Rosen] The processes that control the number and shape of the mitochondria (mitochondrial dynamics) and the removal of damaged mitochondria (mitophagy) have been the subject of intense research. Recent work indicates that these processes may contribute to the pathology associated with cardiac diseases. This review describes some of the key proteins that regulate these processes and their potential as therapeutic targets for cardiac diseases. The Author(s), 2015 Cardiac disease nationallicence Mitochondria nationallicence Mitophagy nationallicence Autophagy nationallicence Fission nationallicence Fusion nationallicence Mitochondrial dynamics nationallicence Heart nationallicence Disatnik Marie-Hélène Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut Hwang Sunhee Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut Ferreira Julio Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, 05508-000, São Paulo, Brazil aut Mochly-Rosen Daria Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut Journal of Molecular Medicine Springer Berlin Heidelberg 93/3(2015-03-01), 279-287 0946-2716 93:3<279 2015 93 109 https://doi.org/10.1007/s00109-015-1256-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00109-015-1256-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Disatnik Marie-Hélène Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 700 1- Hwang Sunhee Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 700 1- Ferreira Julio Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, 05508-000, São Paulo, Brazil aut NATIONALLICENCE 700 1- Mochly-Rosen Daria Department of Chemical and Systems Biology, Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 773 0- Journal of Molecular Medicine Springer Berlin Heidelberg 93/3(2015-03-01), 279-287 0946-2716 93:3<279 2015 93 109