Parental Decisions Following Prenatal Diagnosis of Chromosomal Abnormalities: Implications for Genetic Counseling Practice in Japan
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| 024 | 7 | 0 | |a 10.1007/s10897-014-9744-1 |2 doi |
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| 245 | 0 | 0 | |a Parental Decisions Following Prenatal Diagnosis of Chromosomal Abnormalities: Implications for Genetic Counseling Practice in Japan |h [Elektronische Daten] |c [Nobuhiro Suzumori, Kyoko Kumagai, Shinobu Goto, Akira Nakamura, Mayumi Sugiura-Ogasawara] |
| 520 | 3 | |a Parental decision-making to terminate or continue a pregnancy was studied after prenatal diagnosis of a chromosome aneuploidy among a sample of patients around the city of Nagoya, Japan. A total of 1,051 amniocentesis cases at 15-18weeks of gestation were analyzed. Of these, 60 cases of chromosomal anomalies with aneuploidies were diagnosed by conventional cytogenetic analysis. Of the 45 diagnoses of autosomal chromosome aneuploidies, pregnancy was terminated in 93.3% of the cases. Of the 15 cases diagnosed with sex chromosome aneuploidy, pregnancy was terminated in 46.7%. Differences in parental decisions with respect to maternal age, gestational week at diagnosis, number of pregnancies per individual and existing number of children were not significant in patients diagnosed either with autosomal or sex chromosome aneuploidy. The findings indicate that when diagnosed with a chromosome aneuploidy in which a severe prognosis was expected, most couples decided to terminate the pregnancy in Japan. Implications of these findings for expanding the profession of genetic counseling are discussed and research recommendations are provided. | |
| 540 | |a National Society of Genetic Counselors, Inc., 2014 | ||
| 690 | 7 | |a Prenatal diagnosis |2 nationallicence | |
| 690 | 7 | |a Termination |2 nationallicence | |
| 690 | 7 | |a Genetic counseling |2 nationallicence | |
| 690 | 7 | |a Chromosome aneuploidy |2 nationallicence | |
| 690 | 7 | |a Japan |2 nationallicence | |
| 700 | 1 | |a Suzumori |D Nobuhiro |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | |
| 700 | 1 | |a Kumagai |D Kyoko |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | |
| 700 | 1 | |a Goto |D Shinobu |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | |
| 700 | 1 | |a Nakamura |D Akira |u Chiba University of Commerce, 1-3-1, Konodai, 272-8512, Ichikawa, Chiba, Japan |4 aut | |
| 700 | 1 | |a Sugiura-Ogasawara |D Mayumi |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | |
| 773 | 0 | |t Journal of Genetic Counseling |d Springer US; http://www.springer-ny.com |g 24/1(2015-02-01), 117-121 |x 1059-7700 |q 24:1<117 |1 2015 |2 24 |o 10897 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10897-014-9744-1 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10897-014-9744-1 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Suzumori |D Nobuhiro |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kumagai |D Kyoko |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Goto |D Shinobu |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nakamura |D Akira |u Chiba University of Commerce, 1-3-1, Konodai, 272-8512, Ichikawa, Chiba, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sugiura-Ogasawara |D Mayumi |u Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Genetic Counseling |d Springer US; http://www.springer-ny.com |g 24/1(2015-02-01), 117-121 |x 1059-7700 |q 24:1<117 |1 2015 |2 24 |o 10897 | ||