caa a22 4500 605544352 CHVBK 20210128100931.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10897-015-9826-8 doi (NATIONALLICENCE)springer-10.1007/s10897-015-9826-8 Using ApoE Genotyping to Promote Healthy Lifestyles in Finland - Psychological Impacts: Randomized Controlled Trial [Elektronische Daten] [H.-L. Hietaranta-Luoma, H. Luomala, H. Puolijoki, A. Hopia] Common health recommendations often incite very little public response, as people instead require individualized information. The purpose of this study was to assess the psychological effects of personal genetic information, provided by different apoE genotypes, as a tool to promote lifestyle changes. This study was a one-year intervention study using healthy adults, aged 20-67years (n = 107). Their experiences of state anxiety, threat and stage of change were measured three times over a 12months period. These psychological experiences were assessed, during the genetic information gathering, for three groups: a high-risk group (Ɛ4+, n = 16); a low-risk group (Ɛ4−, n = 35); and a control group (n = 56). The psychological effects of personal genetic risk information were shown to be short-term, although the levels of state anxiety and threat experiences in the high-risk group both remained at a slightly higher level than in the baseline. Threat experiences differed almost significantly (alpha = 0.017) between the Ɛ4+ and Ɛ4− groups (p = 0.034). Information on the apoE genotype impacted the experience of cardiovascular threat; this effect was most intense immediately after genetic feedback was received. However, fears of threat and anxiety may not be an obstacle for using gene information to motivate healthy, stable adults towards making lifestyle changes. Further studies should thus focus on how to utilize genetic screening in prevention of lifestyle-related diseases. National Society of Genetic Counselors, Inc., 2015 Genetic testing nationallicence ApoE nationallicence Intervention nationallicence Anxiety nationallicence Threat nationallicence Stage of change nationallicence Hietaranta-Luoma H.-L Functional Foods Forum, University of Turku, Kampusranta 9 C, 60320, Seinäjoki, Finland aut Luomala H. Department of Marketing, University of Vaasa, Vaasa, Finland aut Puolijoki H. Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland aut Hopia A. Functional Foods Forum, University of Turku, Kampusranta 9 C, 60320, Seinäjoki, Finland aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/6(2015-12-01), 908-921 1059-7700 24:6<908 2015 24 10897 https://doi.org/10.1007/s10897-015-9826-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-015-9826-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hietaranta-Luoma H.-L Functional Foods Forum, University of Turku, Kampusranta 9 C, 60320, Seinäjoki, Finland aut NATIONALLICENCE 700 1- Luomala H. Department of Marketing, University of Vaasa, Vaasa, Finland aut NATIONALLICENCE 700 1- Puolijoki H. Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland aut NATIONALLICENCE 700 1- Hopia A. Functional Foods Forum, University of Turku, Kampusranta 9 C, 60320, Seinäjoki, Finland aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/6(2015-12-01), 908-921 1059-7700 24:6<908 2015 24 10897