A Genetic Lung Cancer Susceptibility Test may have a Positive Effect on Smoking Cessation

Verfasser / Beitragende:
[Tammy Kammin, Andrew Fenton, Kathryn Thirlaway]
Ort, Verlag, Jahr:
2015
Enthalten in:
Journal of Genetic Counseling, 24/3(2015-06-01), 522-531
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10897-014-9766-8  |2 doi 
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245 0 2 |a A Genetic Lung Cancer Susceptibility Test may have a Positive Effect on Smoking Cessation  |h [Elektronische Daten]  |c [Tammy Kammin, Andrew Fenton, Kathryn Thirlaway] 
520 3 |a Smoking increases the risk of developing lung cancer. Genetic loci have been identified which could form the basis of a lung cancer susceptibility test; but little is known whether such a test would interest or motivate those trying to quit smoking. To address this, we investigated the attitudes of people trying to quit smoking towards genetic susceptibility testing for lung cancer. Participant's attitudes to topics associated with lung cancer susceptibility testing were assessed; were they interested in genetic testing? What impact would a hypothetical high- or low- risk result have on smoking cessation? 680 self-completion questionnaires were given to individuals attending National Health Service stop smoking clinics in three different areas of the United Kingdom between 2011 and 2012. 139 questionnaires were returned, giving a 20% response rate. Participants expressed an interest in a genetic susceptibility test for lung cancer and almost all reported that a high-risk result would increase their motivation to stop smoking. However, many participants had a neutral attitude towards a low-risk result. Most participants agreed their smoking habit could lead to lung cancer. Lung cancer susceptibility testing may be a useful incentive to help people quit smoking. This study suggests the need for genetic services to work with smoking cessation teams if routine testing becomes available in the future. 
540 |a National Society of Genetic Counselors, Inc., 2014 
690 7 |a Genetic testing  |2 nationallicence 
690 7 |a Attitude scales  |2 nationallicence 
690 7 |a Lung cancer  |2 nationallicence 
690 7 |a Smoking cessation  |2 nationallicence 
690 7 |a Genetic counseling  |2 nationallicence 
690 7 |a Genetic susceptibility testing  |2 nationallicence 
690 7 |a Transtheoretical model  |2 nationallicence 
700 1 |a Kammin  |D Tammy  |u Institute of Genetic Medicine, International Centre for Life, Central Parkway, Newcastle, UK  |4 aut 
700 1 |a Fenton  |D Andrew  |u Institute for Cell and Molecular Biosciences, Baddiley-Clark Building, Medical School, Newcastle University, Richardson Road, Newcastle-upon-Tyne, UK  |4 aut 
700 1 |a Thirlaway  |D Kathryn  |u Department of Applied Psychology, School of Health Sciences, Cardiff Metropolitan University, Western Avenue, Cardiff, UK  |4 aut 
773 0 |t Journal of Genetic Counseling  |d Springer US; http://www.springer-ny.com  |g 24/3(2015-06-01), 522-531  |x 1059-7700  |q 24:3<522  |1 2015  |2 24  |o 10897 
856 4 0 |u https://doi.org/10.1007/s10897-014-9766-8  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10897-014-9766-8  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kammin  |D Tammy  |u Institute of Genetic Medicine, International Centre for Life, Central Parkway, Newcastle, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fenton  |D Andrew  |u Institute for Cell and Molecular Biosciences, Baddiley-Clark Building, Medical School, Newcastle University, Richardson Road, Newcastle-upon-Tyne, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Thirlaway  |D Kathryn  |u Department of Applied Psychology, School of Health Sciences, Cardiff Metropolitan University, Western Avenue, Cardiff, UK  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Journal of Genetic Counseling  |d Springer US; http://www.springer-ny.com  |g 24/3(2015-06-01), 522-531  |x 1059-7700  |q 24:3<522  |1 2015  |2 24  |o 10897