caa a22 4500 605544573 CHVBK 20210128100932.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10897-014-9766-8 doi (NATIONALLICENCE)springer-10.1007/s10897-014-9766-8 A Genetic Lung Cancer Susceptibility Test may have a Positive Effect on Smoking Cessation [Elektronische Daten] [Tammy Kammin, Andrew Fenton, Kathryn Thirlaway] Smoking increases the risk of developing lung cancer. Genetic loci have been identified which could form the basis of a lung cancer susceptibility test; but little is known whether such a test would interest or motivate those trying to quit smoking. To address this, we investigated the attitudes of people trying to quit smoking towards genetic susceptibility testing for lung cancer. Participant's attitudes to topics associated with lung cancer susceptibility testing were assessed; were they interested in genetic testing? What impact would a hypothetical high- or low- risk result have on smoking cessation? 680 self-completion questionnaires were given to individuals attending National Health Service stop smoking clinics in three different areas of the United Kingdom between 2011 and 2012. 139 questionnaires were returned, giving a 20% response rate. Participants expressed an interest in a genetic susceptibility test for lung cancer and almost all reported that a high-risk result would increase their motivation to stop smoking. However, many participants had a neutral attitude towards a low-risk result. Most participants agreed their smoking habit could lead to lung cancer. Lung cancer susceptibility testing may be a useful incentive to help people quit smoking. This study suggests the need for genetic services to work with smoking cessation teams if routine testing becomes available in the future. National Society of Genetic Counselors, Inc., 2014 Genetic testing nationallicence Attitude scales nationallicence Lung cancer nationallicence Smoking cessation nationallicence Genetic counseling nationallicence Genetic susceptibility testing nationallicence Transtheoretical model nationallicence Kammin Tammy Institute of Genetic Medicine, International Centre for Life, Central Parkway, Newcastle, UK aut Fenton Andrew Institute for Cell and Molecular Biosciences, Baddiley-Clark Building, Medical School, Newcastle University, Richardson Road, Newcastle-upon-Tyne, UK aut Thirlaway Kathryn Department of Applied Psychology, School of Health Sciences, Cardiff Metropolitan University, Western Avenue, Cardiff, UK aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/3(2015-06-01), 522-531 1059-7700 24:3<522 2015 24 10897 https://doi.org/10.1007/s10897-014-9766-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-014-9766-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kammin Tammy Institute of Genetic Medicine, International Centre for Life, Central Parkway, Newcastle, UK aut NATIONALLICENCE 700 1- Fenton Andrew Institute for Cell and Molecular Biosciences, Baddiley-Clark Building, Medical School, Newcastle University, Richardson Road, Newcastle-upon-Tyne, UK aut NATIONALLICENCE 700 1- Thirlaway Kathryn Department of Applied Psychology, School of Health Sciences, Cardiff Metropolitan University, Western Avenue, Cardiff, UK aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/3(2015-06-01), 522-531 1059-7700 24:3<522 2015 24 10897