Disclosing Genetic Information to Family Members About Inherited Cardiac Arrhythmias: An Obligation or a Choice?
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| 024 | 7 | 0 | |a 10.1007/s10897-014-9783-7 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10897-014-9783-7 | ||
| 245 | 0 | 0 | |a Disclosing Genetic Information to Family Members About Inherited Cardiac Arrhythmias: An Obligation or a Choice? |h [Elektronische Daten] |c [Rick Vavolizza, Isha Kalia, Kathleen Aaron, Louise Silverstein, Dorit Barlevy, David Wasserman, Christine Walsh, Robert Marion, Siobhan Dolan] |
| 520 | 3 | |a Inherited cardiac arrhythmias such as long QT syndrome and Brugada syndrome, present clinical as well as ethical, legal, and social challenges. Many individuals who carry a deleterious mutation are largely asymptomatic and therefore may not be diagnosed until after the occurrence of a personal or family member's cardiac event. The familial nature of inherited genetic information raises numerous ethical, legal, and social issues regarding the sharing of genetic information, particularly when an individual found to carry a deleterious mutation refuses to disclose his or her results to at-risk family members who could benefit from life-saving treatments. This qualitative study sought to understand the experiences with genetic testing for individuals (n = 50) with a personal or family history of cardiac events or sudden death. Unstructured in-person focus groups or interviews were conducted for each participant in the study. The recordings of these interviews were transcribed verbatim and subsequently analyzed and coded. Participants' comments regarding sharing of genetic information centered around four main themes: (1) motivation to disclose; (2) extent of disclosure; (3) effect of disclosure on family dynamics; and (4) reasons for not sharing genetic information. The majority of individuals believed that affected individuals are obligated to disclose genetic information to family members. In the era of personalized medicine, the disclosure of genetic information provides individuals the opportunities to learn about the genetics, disease characteristics, and treatment options in order to reduce morbidity and mortality in themselves and their family members. Further research is necessary to identify and explore the barriers to sharing genetic information with at-risk family members. | |
| 540 | |a National Society of Genetic Counselors, Inc., 2014 | ||
| 690 | 7 | |a Disclosing genetic information |2 nationallicence | |
| 690 | 7 | |a Cardiac arrhythmia |2 nationallicence | |
| 690 | 7 | |a Long QT syndrome |2 nationallicence | |
| 690 | 7 | |a Ethical, Legal, and social issues |2 nationallicence | |
| 690 | 7 | |a Genetic counseling |2 nationallicence | |
| 690 | 7 | |a Family communication |2 nationallicence | |
| 700 | 1 | |a Vavolizza |D Rick |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Kalia |D Isha |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Aaron |D Kathleen |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Silverstein |D Louise |u Ferkauf Graduate School of Psychology of Yeshiva University, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Barlevy |D Dorit |u Center for Ethics at Yeshiva University, New York, NY, USA |4 aut | |
| 700 | 1 | |a Wasserman |D David |u Center for Ethics at Yeshiva University, New York, NY, USA |4 aut | |
| 700 | 1 | |a Walsh |D Christine |u Department of Cardiology, Children's Hospital at Montefiore, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Marion |D Robert |u Divisions of Developmental Medicine & Genetics, Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Dolan |D Siobhan |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | |
| 773 | 0 | |t Journal of Genetic Counseling |d Springer US; http://www.springer-ny.com |g 24/4(2015-08-01), 608-615 |x 1059-7700 |q 24:4<608 |1 2015 |2 24 |o 10897 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10897-014-9783-7 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10897-014-9783-7 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vavolizza |D Rick |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kalia |D Isha |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Aaron |D Kathleen |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Silverstein |D Louise |u Ferkauf Graduate School of Psychology of Yeshiva University, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Barlevy |D Dorit |u Center for Ethics at Yeshiva University, New York, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wasserman |D David |u Center for Ethics at Yeshiva University, New York, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Walsh |D Christine |u Department of Cardiology, Children's Hospital at Montefiore, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Marion |D Robert |u Divisions of Developmental Medicine & Genetics, Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dolan |D Siobhan |u Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/ Montefiore Medical Center, 1300 Morris Park Avenue, Block 634, 10461, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Journal of Genetic Counseling |d Springer US; http://www.springer-ny.com |g 24/4(2015-08-01), 608-615 |x 1059-7700 |q 24:4<608 |1 2015 |2 24 |o 10897 | ||