caa a22 4500 605544816 CHVBK 20210128100933.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10897-014-9810-8 doi (NATIONALLICENCE)springer-10.1007/s10897-014-9810-8 Factors Associated with Uptake of Genetics Services for Hypertrophic Cardiomyopathy [Elektronische Daten] [Amirah Khouzam, Andrea Kwan, Samantha Baxter, Jonathan Bernstein] Hypertrophic cardiomyopathy (HCM) is a common cardiovascular disorder with variable expressivity and incomplete penetrance. Clinical guidelines recommend consultation with a genetics professional as part of an initial assessment for HCM, yet there remains an underutilization of genetics services. We conducted a study to assess factors associated with this underutilization within the framework of the Health Belief Model (HBM). An online survey was completed by 306 affected individuals and at risk family members. Thirty-seven percent of individuals (113/306) had visited a genetics professional for reasons related to HCM. Genetic testing was performed on 53% (162/306). Individuals who had undergone testing were more likely to have seen a genetics professional (p < 0.001), had relatives with an HCM diagnosis (p = 0.002), and have a known familial mutation (p < 0.001). They were also more likely to agree that genetic testing would satisfy their curiosity (p < 0.001), provide reassurance (p < 0.001), aid family members in making healthcare decisions (p < 0.001), and encourage them to engage in a healthier lifestyle (p = 0.002). The HBM components of cues to action and perceived benefits and barriers had the greatest impact on uptake of genetic testing. In order to ensure optimal counseling and care for individuals and families with HCM, awareness and education around HCM and genetic services should be promoted in both physicians and patients alike. National Society of Genetic Counselors, Inc., 2015 Hypertrophic cardiomyopathy (HCM) nationallicence Genetic testing nationallicence Genetic services nationallicence Utilization nationallicence Health Belief Model nationallicence Khouzam Amirah Department of Genetics, Stanford University, Stanford, CA, USA aut Kwan Andrea Department of Genetics, Stanford University, Stanford, CA, USA aut Baxter Samantha Laboratory for Molecular Medicine, Partners HealthCare Center for Personalized Genetic Medicine, Cambridge, MA, USA aut Bernstein Jonathan Department of Pediatrics, Division of Medical Genetics, Stanford University, 300 Pasteur Dr. H-315, 94305, Stanford, CA, USA aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 797-809 1059-7700 24:5<797 2015 24 10897 https://doi.org/10.1007/s10897-014-9810-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-014-9810-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khouzam Amirah Department of Genetics, Stanford University, Stanford, CA, USA aut NATIONALLICENCE 700 1- Kwan Andrea Department of Genetics, Stanford University, Stanford, CA, USA aut NATIONALLICENCE 700 1- Baxter Samantha Laboratory for Molecular Medicine, Partners HealthCare Center for Personalized Genetic Medicine, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Bernstein Jonathan Department of Pediatrics, Division of Medical Genetics, Stanford University, 300 Pasteur Dr. H-315, 94305, Stanford, CA, USA aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 797-809 1059-7700 24:5<797 2015 24 10897