caa a22 4500 605544824 CHVBK 20210128100933.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10897-015-9822-z doi (NATIONALLICENCE)springer-10.1007/s10897-015-9822-z Do Attachment Style and Emotion Regulation Strategies Indicate Distress in Predictive Testing? [Elektronische Daten] [Lucienne van der Meer, Erik van Duijn, Erik Giltay, Aad Tibben] Predictive genetic testing for a neurogenetic disorder evokes strong emotions, and may lead to distress. The aim of this study is to investigate whether attachment style and emotion regulation strategies are associated with distress in persons who present for predictive testing for a neurogenetic disorder, and whether these psychological traits predict distress after receiving test results. Self-report scales were used to assess attachment insecurity (anxiety and avoidance) and maladaptive emotion regulation strategies (self-blame, rumination, catastrophizing) in adults at 50% risk for Huntington's Disease (HD), Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), and Hereditary Cerebral Hemorrhage With Amyloidosis - Dutch type (HCHWA-D), when they presented for predictive testing. Distress was measured before testing and twice (within 2months and between 6 and 8months) after receiving test results. Pearson correlations and linear regression were used to analyze whether attachment style and emotion regulation strategies indicated distress. In 98 persons at risk for HD, CADASIL, or HCHWA-D, attachment anxiety and catastrophizing were associated with distress before predictive testing. Attachment anxiety predicted distress up to 2months after testing. Clinicians may consider looking for signs of attachment anxiety and catastrophizing in persons who present for predictive testing, to see who may be vulnerable for distress during and after testing. The Author(s), 2015 Attachment style nationallicence Emotion regulation strategies nationallicence Predictive testing nationallicence Neurogenetic disorders nationallicence Huntington's disease nationallicence CADASIL nationallicence HCHWA-D nationallicence Distress nationallicence van der Meer Lucienne Department of Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut van Duijn Erik Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut Giltay Erik Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut Tibben Aad Department of Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 862-871 1059-7700 24:5<862 2015 24 10897 https://doi.org/10.1007/s10897-015-9822-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-015-9822-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van der Meer Lucienne Department of Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut NATIONALLICENCE 700 1- van Duijn Erik Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut NATIONALLICENCE 700 1- Giltay Erik Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut NATIONALLICENCE 700 1- Tibben Aad Department of Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300, Leiden, RC, The Netherlands aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 862-871 1059-7700 24:5<862 2015 24 10897