caa a22 4500 605544921 CHVBK 20210128100933.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s10897-014-9817-1 doi (NATIONALLICENCE)springer-10.1007/s10897-014-9817-1 Association of Researcher Characteristics with Views on Return of Incidental Findings from Genomic Research [Elektronische Daten] [Julia Wynn, Josue Martinez, Jimmy Duong, Yuan Zhang, Jo Phelan, Abby Fyer, Robert Klitzman, Paul Appelbaum, Wendy Chung] Whole exome/ genome sequencing (WES/WGS) is now commonly used in research and is increasingly used in clinical care to identify the genetic basis of rare and unknown diseases. The management of incidental findings (IFs) generated through these analyses is debated within the research community. To examine how views regarding genomic research IFs are associated with researcher characteristics and experiences, we surveyed genetic professionals and assessed the effect of professional background and experience on their opinions. Researchers who did not have clinical training, provide clinical care to research participants, or have prior experience returning research results were in general more inclined to offer return of IFs than their colleagues with these characteristics. Understanding this will be important to fully appreciate the impact that policies on return of genetic IFs could have on participants, researchers, and genomic research. National Society of Genetic Counselors, Inc., 2015 Genetics research nationallicence Genomics nationallicence Genomic results nationallicence Incidental findings nationallicence Return of results nationallicence Secondary findings nationallicence Whole exome sequencing nationallicence Wynn Julia Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut Martinez Josue Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut Duong Jimmy Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA aut Zhang Yuan Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA aut Phelan Jo Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA aut Fyer Abby Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut Klitzman Robert Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut Appelbaum Paul Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut Chung Wendy Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 833-841 1059-7700 24:5<833 2015 24 10897 https://doi.org/10.1007/s10897-014-9817-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-014-9817-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wynn Julia Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut NATIONALLICENCE 700 1- Martinez Josue Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut NATIONALLICENCE 700 1- Duong Jimmy Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA aut NATIONALLICENCE 700 1- Zhang Yuan Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA aut NATIONALLICENCE 700 1- Phelan Jo Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA aut NATIONALLICENCE 700 1- Fyer Abby Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut NATIONALLICENCE 700 1- Klitzman Robert Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut NATIONALLICENCE 700 1- Appelbaum Paul Department of Psychiatry, Columbia University Medical Center and NY State Psychiatric Institute, New York, NY, USA aut NATIONALLICENCE 700 1- Chung Wendy Department of Pediatrics, Columbia University Medical Center, 1150 St. Nicholas Ave., Russ Berrie Pavilion, 6th Fl, Rm 620, 10032, New York, NY, USA aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/5(2015-10-01), 833-841 1059-7700 24:5<833 2015 24 10897