caa a22 4500 605545022 CHVBK 20210128100934.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10897-014-9804-6 doi (NATIONALLICENCE)springer-10.1007/s10897-014-9804-6 How Can Psychological Science Inform Research About Genetic Counseling for Clinical Genomic Sequencing? [Elektronische Daten] [Cynthia Khan, Christine Rini, Barbara Bernhardt, J. Roberts, Kurt Christensen, James Evans, Kyle Brothers, Myra Roche, Jonathan Berg, Gail Henderson] Next generation genomic sequencing technologies (including whole genome or whole exome sequencing) are being increasingly applied to clinical care. Yet, the breadth and complexity of sequencing information raise questions about how best to communicate and return sequencing information to patients and families in ways that facilitate comprehension and optimal health decisions. Obtaining answers to such questions will require multidisciplinary research. In this paper, we focus on how psychological science research can address questions related to clinical genomic sequencing by explaining emotional, cognitive, and behavioral processes in response to different types of genomic sequencing information (e.g., diagnostic results and incidental findings). We highlight examples of psychological science that can be applied to genetic counseling research to inform the following questions: (1) What factors influence patients' and providers' informational needs for developing an accurate understanding of what genomic sequencing results do and do not mean?; (2) How and by whom should genomic sequencing results be communicated to patients and their family members?; and (3) How do patients and their families respond to uncertainties related to genomic information? National Society of Genetic Counselors, Inc., 2014 Communication nationallicence Genome sequencing nationallicence Patient understanding nationallicence Psychological nationallicence Psychosocial nationallicence Khan Cynthia Department of Health Behavior, University of North Carolina-Chapel Hill, 312 Rosenau Hall, CB#7440, 27599-7440, Chapel Hill, NC, USA aut Rini Christine Health Behavior, Lineberger Comprehensive Cancer Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut Bernhardt Barbara Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA aut Roberts J. Health Behavior & Health Education, Center for Bioethics and Social Sciences in Medicine, University of Michigan-Ann Arbor, Ann Arbor, MI, USA aut Christensen Kurt Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA aut Evans James Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut Brothers Kyle Family and Geriatric Medicine, University of Louisville School of Medicine, Louisville, KY, USA aut Roche Myra Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut Berg Jonathan Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut Henderson Gail Social Medicine, Center for Genomics & Society, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/2(2015-04-01), 193-204 1059-7700 24:2<193 2015 24 10897 https://doi.org/10.1007/s10897-014-9804-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10897-014-9804-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khan Cynthia Department of Health Behavior, University of North Carolina-Chapel Hill, 312 Rosenau Hall, CB#7440, 27599-7440, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Rini Christine Health Behavior, Lineberger Comprehensive Cancer Center, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Bernhardt Barbara Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Roberts J. Health Behavior & Health Education, Center for Bioethics and Social Sciences in Medicine, University of Michigan-Ann Arbor, Ann Arbor, MI, USA aut NATIONALLICENCE 700 1- Christensen Kurt Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Evans James Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Brothers Kyle Family and Geriatric Medicine, University of Louisville School of Medicine, Louisville, KY, USA aut NATIONALLICENCE 700 1- Roche Myra Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Berg Jonathan Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Henderson Gail Social Medicine, Center for Genomics & Society, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA aut NATIONALLICENCE 773 0- Journal of Genetic Counseling Springer US; http://www.springer-ny.com 24/2(2015-04-01), 193-204 1059-7700 24:2<193 2015 24 10897