caa a22 4500 605545553 CHVBK 20210128100936.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00723-015-0680-5 doi (NATIONALLICENCE)springer-10.1007/s00723-015-0680-5 Improved Stability and Spectral Quality in Ex Situ Dissolution DNP Using an Improved Transfer Device [Elektronische Daten] [Sotirios Katsikis, Ildefonso Marin-Montesinos, Miquel Pons, Christian Ludwig, Ulrich Günther] Dissolution dynamic nuclear polarization (DNP) has become one of the predominant implementations for DNP. However, the technical implementation of transferring the sample from the polarizer to the nuclear magnetic resonance (NMR) system remains challenging. There is a need for additional technical optimizations in order to use dissolution DNP for biochemical and chemical applications. Here we show how a newly designed pressure dissolution kit considerably improves spectral quality and stability by enabling highly reliable and fast sample transfer to the NMR system. Springer-Verlag Wien, 2015 Katsikis Sotirios School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut Marin-Montesinos Ildefonso Biomolecular NMR Laboratory, Organic Chemistry Department, University of Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain aut Pons Miquel Biomolecular NMR Laboratory, Organic Chemistry Department, University of Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain aut Ludwig Christian School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut Günther Ulrich School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut Applied Magnetic Resonance Springer Vienna 46/7(2015-07-01), 723-729 0937-9347 46:7<723 2015 46 723 https://doi.org/10.1007/s00723-015-0680-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00723-015-0680-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Katsikis Sotirios School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut NATIONALLICENCE 700 1- Marin-Montesinos Ildefonso Biomolecular NMR Laboratory, Organic Chemistry Department, University of Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain aut NATIONALLICENCE 700 1- Pons Miquel Biomolecular NMR Laboratory, Organic Chemistry Department, University of Barcelona, Martí i Franquès 1-11, 08028, Barcelona, Spain aut NATIONALLICENCE 700 1- Ludwig Christian School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut NATIONALLICENCE 700 1- Günther Ulrich School of Cancer Sciences, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK aut NATIONALLICENCE 773 0- Applied Magnetic Resonance Springer Vienna 46/7(2015-07-01), 723-729 0937-9347 46:7<723 2015 46 723