caa a22 4500 605545855 CHVBK 20210128100938.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00723-015-0708-x doi (NATIONALLICENCE)springer-10.1007/s00723-015-0708-x Hemodynamic Effects of Pathological Tortuosity of the Internal Carotid Arteries Based on MRI and Ultrasound Studies [Elektronische Daten] [Yu. Stankevich, M. Rezakova, O. Bogomyakova, L. Shraybman, A. Tulupov] Our study was designed to determine the effect of different forms of pathological tortuosity of the internal carotid arteries on the formation of hemodynamic flow profile. Using a 1.5T magnetic resonance imaging (MRI) device, 50 healthy volunteers and 43 patients with pathological tortuosity of the internal carotid arteries were studied by applying routine MRI protocol and quantitative phase-contrast MR angiography. Changes in the peak, linear and volumetric blood flow rates as well as the cross-sectional areas of the vessel were measured during the cardiac cycle within the cervical and intracranial segments of the internal carotid arteries. 20 patients with pathological tortuosity of the internal carotid arteries were subjected to ultrasound study. In both, the control group and the group with pathological tortuosity, the shape of the curves that reflects the change in the linear blood flow rate as a function of the cardiac cycle, obtained with ultrasound and MRI, qualitatively coincides and does not depend on the tested segment of the artery and its path. The correlation coefficient was low between the peak blood flow rate obtained by ultrasound and MRI. The quantitative values of the blood flow rate, obtained in the control group and the group with pathological tortuosity, differed significantly in different segments of the internal carotid arteries. However, no significant differences were observed in blood flow rates between various forms of ICA tortuosity. The cross-sectional area was significantly higher in the case of pathological tortuosity of the internal carotid arteries as compared to the control group. Springer-Verlag Wien, 2015 Stankevich Yu The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut Rezakova M. StateResearch Institute ofPhysiology and Fundamental Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Timakova, 4, 630117, Novosibirsk, Russian Federation aut Bogomyakova O. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut Shraybman L. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut Tulupov A. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut Applied Magnetic Resonance Springer Vienna 46/10(2015-10-01), 1109-1120 0937-9347 46:10<1109 2015 46 723 https://doi.org/10.1007/s00723-015-0708-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00723-015-0708-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stankevich Yu The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut NATIONALLICENCE 700 1- Rezakova M. StateResearch Institute ofPhysiology and Fundamental Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Timakova, 4, 630117, Novosibirsk, Russian Federation aut NATIONALLICENCE 700 1- Bogomyakova O. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut NATIONALLICENCE 700 1- Shraybman L. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut NATIONALLICENCE 700 1- Tulupov A. The Institute International Tomography Center of the Russian Academy of Sciences, Institutskaya, 3a, 630090, Novosibirsk, Russian Federation aut NATIONALLICENCE 773 0- Applied Magnetic Resonance Springer Vienna 46/10(2015-10-01), 1109-1120 0937-9347 46:10<1109 2015 46 723