caa a22 4500 605546185 CHVBK 20210128100939.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00723-014-0629-0 doi (NATIONALLICENCE)springer-10.1007/s00723-014-0629-0 Optimized Phase-Sensitive Inversion Recovery for MRI Contrast Manipulation [Elektronische Daten] [Yan Chang, Daxiu Wei, Steffen Glaser, Xiaodong Yang] In this paper, we propose a practical optimized phase-sensitive inversion recovery approach for longitudinal contrast enhancement of tissues. With the usage of double dynamic range of longitudinal magnetization, the contrast of tissues can be maximized with an optimal inversion pulse, which is optimized by an extended version of optimal-control-based gradient ascent method. Moreover, to demonstrate this optimized contrast, a modified image reconstruction of region-growing spin reversal operation is presented. Simulation experiments show that even for tissues with same $$T_{1}$$ T 1 value, the contrast can be increased up to 28 $$\%$$ % compared with the saturation contrast enhancement. It has a great potential for enhancing contrast of tissues, and in particular, of limited intrinsic different tissues. Springer-Verlag Wien, 2015 Chang Yan Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 215163, Suzhou, Jiangsu, China aut Wei Daxiu Physics Department and Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, 200062, Shanghai, China aut Glaser Steffen Department of Chemistry, Technische Universität München, 85747, Garching, Germany aut Yang Xiaodong Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 215163, Suzhou, Jiangsu, China aut Applied Magnetic Resonance Springer Vienna 46/2(2015-02-01), 203-217 0937-9347 46:2<203 2015 46 723 https://doi.org/10.1007/s00723-014-0629-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00723-014-0629-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chang Yan Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 215163, Suzhou, Jiangsu, China aut NATIONALLICENCE 700 1- Wei Daxiu Physics Department and Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, 200062, Shanghai, China aut NATIONALLICENCE 700 1- Glaser Steffen Department of Chemistry, Technische Universität München, 85747, Garching, Germany aut NATIONALLICENCE 700 1- Yang Xiaodong Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 215163, Suzhou, Jiangsu, China aut NATIONALLICENCE 773 0- Applied Magnetic Resonance Springer Vienna 46/2(2015-02-01), 203-217 0937-9347 46:2<203 2015 46 723