caa a22 4500 606154019 CHVBK 20210128100556.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s11121-014-0478-y doi (NATIONALLICENCE)springer-10.1007/s11121-014-0478-y Prevention Trial in the Cherokee Nation: Design of a Randomized Community Trial [Elektronische Daten] [Kelli Komro, Alexander Wagenaar, Misty Boyd, B. Boyd, Terrence Kominsky, Dallas Pettigrew, Amy Tobler, Sarah Lynne-Landsman, Melvin Livingston, Bethany Livingston, Mildred Molina] Despite advances in prevention science and practice in recent decades, the U.S. continues to struggle with significant alcohol-related risks and consequences among youth, especially among vulnerable rural and Native American youth. The Prevention Trial in the Cherokee Nation is a partnership between prevention scientists and Cherokee Nation Behavioral Health to create, implement, and evaluate a new, integrated community-level intervention designed to prevent underage drinking and associated negative consequences among Native American and other youth living in rural high-risk underserved communities. The intervention builds directly on results of multiple previous trials of two conceptually distinct approaches. The first is an updated version of CMCA, an established community environmental change intervention, and the second is CONNECT, our newly developed population-wide intervention based on screening, brief intervention, and referral to treatment (SBIRT) research. CMCA direct-action community organizing is used to engage local citizens to address community norms and practices related to alcohol use and commercial and social access to alcohol among adolescents. The new CONNECT intervention expands traditional SBIRT to be implemented universally within schools. Six key research design elements optimize causal inference and experimental evaluation of intervention effects, including a controlled interrupted time-series design, purposive selection of towns, random assignment to study condition, nested cohorts as well as repeated cross-sectional observations, a factorial design crossing two conceptually distinct interventions, and multiple comparison groups. The purpose of this paper is to describe the strong partnership between prevention scientists and behavioral health leaders within the Cherokee Nation, and the intervention and research design of this new community trial. The Author(s), 2014 Alcohol prevention nationallicence Native American nationallicence Rural nationallicence Community trial nationallicence SBIRT nationallicence Environment nationallicence Komro Kelli Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Wagenaar Alexander Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Boyd Misty Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut Boyd B. Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut Kominsky Terrence Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut Pettigrew Dallas Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut Tobler Amy Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Lynne-Landsman Sarah Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Livingston Melvin Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Livingston Bethany Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Molina Mildred Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut Prevention Science Springer US; http://www.springer-ny.com 16/2(2015-02-01), 291-300 1389-4986 16:2<291 2015 16 11121 https://doi.org/10.1007/s11121-014-0478-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11121-014-0478-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Komro Kelli Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Wagenaar Alexander Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Boyd Misty Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut NATIONALLICENCE 700 1- Boyd B. Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut NATIONALLICENCE 700 1- Kominsky Terrence Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut NATIONALLICENCE 700 1- Pettigrew Dallas Cherokee Nation Behavioral Health, Tahlequah, OK, USA aut NATIONALLICENCE 700 1- Tobler Amy Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Lynne-Landsman Sarah Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Livingston Melvin Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Livingston Bethany Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Molina Mildred Department of Health Outcomes & Policy, College of Medicine and Institute for Child Health Policy, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 773 0- Prevention Science Springer US; http://www.springer-ny.com 16/2(2015-02-01), 291-300 1389-4986 16:2<291 2015 16 11121