caa a22 4500 606154140 CHVBK 20210128100557.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s11121-014-0474-2 doi (NATIONALLICENCE)springer-10.1007/s11121-014-0474-2 Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length [Elektronische Daten] [Gene Brody, Tianyi Yu, Steven Beach, Robert Philibert] Telomere length (TL) is an indicator of general systemic aging, with diminished TL associated with several chronic diseases of aging and with heightened mortality risk. Research has begun to focus on the ways in which stress contributes to telomere attrition. The purposes of this study were (a) to establish whether exposure to nonsupportive parenting, defined as high levels of conflict and rancor with low levels of warmth and emotional support, at age 17 would forecast TL 5years later; and (b) to determine whether participation in an efficacious family-centered prevention program could ameliorate any associations that emerged. Rural African American adolescents participated in the Adults in the Making (AIM) program or a control condition. Primary caregivers provided data on nonsupportive parenting during a pretest when adolescents were age 17. Adolescents provided data on anger at the pretest and at a posttest administered 7months later. When the youths were age 22, TL was assayed from a blood draw. The results indicated that heightened nonsupportive parenting forecast diminished TL among young adults in the control condition but not among those who participated in AIM; socioeconomic status risk, life stress, and the use of alcohol and cigarettes at age 17, and blood pressure and body mass index at age 22, were controlled. Subsequent exploratory analyses suggested that AIM-induced reductions in adolescents' anger served as a mediator connecting group assignment to TL. The results suggest that the cellular-level sequelae of nonsupportive parenting and stress are not immutable. Society for Prevention Research, 2014 Health promotion nationallicence Parent-child relations nationallicence Stress nationallicence Psychological nationallicence Telomere shortening nationallicence Brody Gene Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut Yu Tianyi Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut Beach Steven Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut Philibert Robert Department of Psychiatry, University of Iowa, Iowa City, IA, USA aut Prevention Science Springer US; http://www.springer-ny.com 16/2(2015-02-01), 171-180 1389-4986 16:2<171 2015 16 11121 https://doi.org/10.1007/s11121-014-0474-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11121-014-0474-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brody Gene Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut NATIONALLICENCE 700 1- Yu Tianyi Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut NATIONALLICENCE 700 1- Beach Steven Center for Family Research, University of Georgia, 1095 College Station Road, 30602-4527, Athens, Georgia aut NATIONALLICENCE 700 1- Philibert Robert Department of Psychiatry, University of Iowa, Iowa City, IA, USA aut NATIONALLICENCE 773 0- Prevention Science Springer US; http://www.springer-ny.com 16/2(2015-02-01), 171-180 1389-4986 16:2<171 2015 16 11121