caa a22 4500 606154450 CHVBK 20210128100558.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10561-013-9413-x doi (NATIONALLICENCE)springer-10.1007/s10561-013-9413-x Dependence of optical attenuation coefficient and mechanical tension of irradiated human cartilage measured by optical coherence tomography [Elektronische Daten] [A. Martinho Junior, A. Freitas, M. Raele, S. Santin, F. Soares, M. Herson, M. Mathor] As banked human tissues are not widely available, the development of new non-destructive and contactless techniques to evaluate the quality of allografts before distribution for transplantation is very important. Also, tissues will be processed accordingly to standard procedures and to minimize disease transmission most tissue banks will include a decontamination or sterilization step such as ionizing radiation. In this work, we present a new method to evaluate the internal structure of frozen or glycerol-processed human cartilages, submitted to various dosis of irradiation, using the total optical attenuation coefficient retrieved from optical coherence tomography (OCT) images. Our results show a close relationship between tensile properties and the total optical attenuation coefficient of cartilages. Therefore, OCT associated with the total optical attenuation coefficient open a new window to evaluate quantitatively biological changes in processed tissues. Springer Science+Business Media Dordrecht, 2013 Cartilage nationallicence Biomechanical nationallicence Optical coherence tomography nationallicence Martinho Junior A. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Freitas A. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Raele M. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Santin S. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Soares F. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Herson M. The Alfred Skin Cell Culture Laboratory, Monash University, Melbourne, Australia aut Mathor M. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut Cell and Tissue Banking Springer Netherlands 16/1(2015-03-01), 47-53 1389-9333 16:1<47 2015 16 10561 https://doi.org/10.1007/s10561-013-9413-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10561-013-9413-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Martinho Junior A. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 700 1- Freitas A. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 700 1- Raele M. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 700 1- Santin S. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 700 1- Soares F. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 700 1- Herson M. The Alfred Skin Cell Culture Laboratory, Monash University, Melbourne, Australia aut NATIONALLICENCE 700 1- Mathor M. Instituto de Pesquisas Energéticas e Nucleares (Ipen/CNEN-SP), São Paulo, Brazil aut NATIONALLICENCE 773 0- Cell and Tissue Banking Springer Netherlands 16/1(2015-03-01), 47-53 1389-9333 16:1<47 2015 16 10561