caa a22 4500 606154531 CHVBK 20210128100559.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10561-014-9481-6 doi (NATIONALLICENCE)springer-10.1007/s10561-014-9481-6 Comparative study of indigenously prepared and imported, demineralized, freeze-dried, irradiated bone allograft in the treatment of periodontal infrabony defects [Elektronische Daten] [Monali Shah, Astrid Lobo Gajiwala, Sneha Shah, Deepak Dave] Demineralized freeze-dried bone allograft (DFDBA) has been used extensively in periodontal therapy. Questions have been raised however, about the osteogenic potential of the variety of grafts available. In India the cost factor is another important consideration. The aim of this study therefore was to evaluate the clinical efficiency of the low priced, indigenously prepared DFDBA obtained from the Tata Memorial Hospital (TMH) Tissue Bank, in periodontal regeneration in infrabony periodontal defects, as compared to DFDBA obtained from the Pacific Coast Tissue Bank (DEMBONE). The latter was used as the control. 16 patients with bilaterally similar periodontal infrabony defects were selected, and randomly allotted to the test and control groups. At baseline, using standardized protocol, recession, probing depths (PD), and clinical attachment levels (CAL) were measured, following which periodontal surgery was carried out, with placement of the respective graft materials. Patients were recalled after 6months for re-assessment. Statistically significant improvement was obtained for PD reduction and CAL gain for both groups (p<0.05). However, no significant difference was observed between the test and control groups. It was therefore concluded that both the materials from different tissue banks are equally effective clinically, with the test material being additionally cost effective. Springer Science+Business Media Dordrecht, 2014 DFDBA nationallicence Demineralized freeze dried bone allograft nationallicence DEMBONE nationallicence Tata Memorial Hospital Tissue Bank nationallicence Periodontal regeneration nationallicence Periodontal infrabony defects nationallicence DFDBA : Demineralized freeze-dried bone allograft nationallicence TMH : Tata Memorial Hospital nationallicence OFD : Open flap debridement nationallicence LA : Local anesthesia nationallicence PD : Probing depth nationallicence CAL : Clinical attachment level nationallicence BMP : Bone morphogenetic protein nationallicence Shah Monali Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut Lobo Gajiwala Astrid Tissue Bank, Tata Memorial Hospital, Dr. E. Borges Road, 400 012, Mumbai, India aut Shah Sneha Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut Dave Deepak Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut Cell and Tissue Banking Springer Netherlands 16/3(2015-09-01), 371-379 1389-9333 16:3<371 2015 16 10561 https://doi.org/10.1007/s10561-014-9481-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10561-014-9481-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shah Monali Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut NATIONALLICENCE 700 1- Lobo Gajiwala Astrid Tissue Bank, Tata Memorial Hospital, Dr. E. Borges Road, 400 012, Mumbai, India aut NATIONALLICENCE 700 1- Shah Sneha Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut NATIONALLICENCE 700 1- Dave Deepak Department of Periodontics, K. M. Shah Dental College and Hospital, Vadodara, India aut NATIONALLICENCE 773 0- Cell and Tissue Banking Springer Netherlands 16/3(2015-09-01), 371-379 1389-9333 16:3<371 2015 16 10561