caa a22 4500 606154876 CHVBK 20210128100600.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10561-015-9511-z doi (NATIONALLICENCE)springer-10.1007/s10561-015-9511-z Non-injected illicit drug use and infectious disease risk of donor tissue: a single institution retrospective review [Elektronische Daten] [Mark Barton Jr., Amir Qureshi, Anita Vijapura, H. Temple] This study assessed the relationship of non-injected illicit drug use and infectious disease seropositivity for human immunodeficiency virus (HIV-1), hepatitis B virus (HBV), hepatitis C virus (HCV), and Syphilis. In a retrospective review of 986 donor charts recovered from 2009 to 2011 at a single tissue bank, the absence of reported non-injected illicit drug use corresponded with seropositivity in 6.61%, of recovered donors while reported illicit drug use in the medical and social history corresponded with seropositivity in 11.25%, representing a 70% increased risk. There was no significant difference noted for overall seropositivity rates between types on noninjected illicit drugs, although donors that used cocaine had a higher incidence of HIV, while marijuana use was associated with a higher rate of HBV, HCV, and syphilis positivity. Toxicology screening results were not an accurate predictor of seropositivity (PPV=3.77%; NPV=91.56%). Further, the degree of relationship between the donor and the next of kin had no bearing on the veracity of actual drug use when comparing the response of the medical-social history and the toxicology screen. Springer Science+Business Media Dordrecht, 2015 Tissue banking nationallicence Seropositivity nationallicence Illicit drug use nationallicence Barton Jr. Mark University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut Qureshi Amir University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut Vijapura Anita St. George's University School of Medicine, St. George's, Grenada aut Temple H. University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut Cell and Tissue Banking Springer Netherlands 16/4(2015-12-01), 623-629 1389-9333 16:4<623 2015 16 10561 https://doi.org/10.1007/s10561-015-9511-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10561-015-9511-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Barton Jr Mark University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut NATIONALLICENCE 700 1- Qureshi Amir University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut NATIONALLICENCE 700 1- Vijapura Anita St. George's University School of Medicine, St. George's, Grenada aut NATIONALLICENCE 700 1- Temple H. University of Miami Miller School of Medicine, 33136, Miami, FL, USA aut NATIONALLICENCE 773 0- Cell and Tissue Banking Springer Netherlands 16/4(2015-12-01), 623-629 1389-9333 16:4<623 2015 16 10561