caa a22 4500 606154981 CHVBK 20210128100601.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10561-014-9469-2 doi (NATIONALLICENCE)springer-10.1007/s10561-014-9469-2 Banking of cryopreserved iliac artery and vein homografts: clinical uses in transplantation [Elektronische Daten] [Wee Heng, Krishnakumar Madhavan, Priscilla Wee, Tracy Seck, Yeong Lim, Chong Lim] Iliac artery and vein homografts are critical for revascularization in living-donor liver transplantation. Since 2010, National Cardiovascular Homograft Bank and National University Hospital have collaborated in the pioneer endeavor of banking iliac vessel homografts for such surgeries in Singapore. This article aims to demonstrate that the processing, decontamination and cryopreservation techniques that our bank follow, help preserve iliac vessel homografts for a longer duration as compared to homografts preserved using short-term preservation techniques. This paper reports the first 4years of post-operative outcome for recipients as a preliminary report for a longer-term outcome study. Criteria for donor assessment, techniques of iliac vessel homograft recovery, processing, decontamination, cryopreservation and storage according to the American Association of Tissue Banks standards are also described. From 2010 until 2013, we discovered of the iliac vessel homografts processed, 17 (94.4%) were suitable for clinical use. Nine iliac artery grafts (64%) and one iliac vein graft (14%) were implanted. Irrespective of vessel type, homografts <90mm in length were of little use. Of the nine current iliac vessel homograft recipients, eight patients (89%) had living-donor liver transplantation and one patient (11%) had reconstruction of the right internal carotid artery after resection of an aneurysm. Our preliminary results supports existing literatures that suggest cryopreserved iliac vessel homografts can be successfully used for revascularization in liver transplantation and reconstruction of carotid artery. Encouraging short-term post-operative patient outcomes have been achieved, with no report of adverse event attributed to implanted homografts. We believe that our processing, decontamination and cryopreservation techniques have helped preserve the homografts for longer duration as compared to homografts preserved using short-term preservation techniques. The Author(s), 2014 Liver transplantation nationallicence Allografts nationallicence Artery nationallicence Vein nationallicence Cryopreservation nationallicence Heng Wee National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut Madhavan Krishnakumar National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore aut Wee Priscilla National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore aut Seck Tracy National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut Lim Yeong National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut Lim Chong National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut Cell and Tissue Banking Springer Netherlands 16/2(2015-06-01), 235-242 1389-9333 16:2<235 2015 16 10561 https://doi.org/10.1007/s10561-014-9469-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10561-014-9469-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heng Wee National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut NATIONALLICENCE 700 1- Madhavan Krishnakumar National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore aut NATIONALLICENCE 700 1- Wee Priscilla National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore aut NATIONALLICENCE 700 1- Seck Tracy National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut NATIONALLICENCE 700 1- Lim Yeong National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut NATIONALLICENCE 700 1- Lim Chong National Cardiovascular Homograft Bank, National Heart Centre Singapore, Singapore, Singapore aut NATIONALLICENCE 773 0- Cell and Tissue Banking Springer Netherlands 16/2(2015-06-01), 235-242 1389-9333 16:2<235 2015 16 10561