caa a22 4500 606155570 CHVBK 20210128100604.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10096-015-2345-6 doi (NATIONALLICENCE)springer-10.1007/s10096-015-2345-6 Common isolation of New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae in a large surgical hospital in Vietnam [Elektronische Daten] [H. Tran, S. Ehsani, K. Shibayama, M. Matsui, S. Suzuki, M. Nguyen, D. Tran, V. Tran, D. Tran, H. Nguyen, D. Dang, H. Trinh, T. Nguyen, H. Wertheim] This study sought to monitor the presence of carbapenem-resistant Enterobacteriaceae (CRE) and the proportion New Delhi metallo-beta-lactamase 1 (NDM-1)-producing bacteria between August 2010 and December 2012 in a surgical hospital in Vietnam. We identified 47 CRE strains from a total of 4,096 Enterobacteriaceae isolates (1.1%) that were NDM-1-positive from 45 patients admitted to 11 different departments, with the majority being from the urology department. The NDM-1 gene was found in seven different species. Genotyping revealed limited clonality of NDM-1-positive isolates. Most of the isolates carried the NDM-1 gene on a plasmid and 17.8% (8/45) of those were readily transferable. We found five patients at admission and one patient at discharge with NDM-1-positive bacteria in their stool. From 200 screening environmental hospital samples, five were confirmed to be NDM-1-positive and included Acinetobacter species (n = 3) and Enterobacter aerogenes (n = 2). The results reveal that NDM-1-producing Enterobacteriaceae are commonly isolated in patients admitted to a Vietnamese surgical hospital and are also detected in the hospital environment. The Author(s), 2015 Tran H. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Ehsani S. Pasteur Institute, Paris, France aut Shibayama K. National Institute of Infectious Diseases, Tokyo, Japan aut Matsui M. National Institute of Infectious Diseases, Tokyo, Japan aut Suzuki S. National Institute of Infectious Diseases, Tokyo, Japan aut Nguyen M. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Tran D. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Tran V. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Nguyen H. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Dang D. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Trinh H. Viet-Duc Hospital, Hanoi, Vietnam aut Nguyen T. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut Wertheim H. Wellcome Trust Major Overseas Program, Oxford University Clinical Research Unit, Hanoi, Vietnam aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/6(2015-06-01), 1247-1254 0934-9723 34:6<1247 2015 34 10096 https://doi.org/10.1007/s10096-015-2345-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-015-2345-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tran H. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Ehsani S. Pasteur Institute, Paris, France aut NATIONALLICENCE 700 1- Shibayama K. National Institute of Infectious Diseases, Tokyo, Japan aut NATIONALLICENCE 700 1- Matsui M. National Institute of Infectious Diseases, Tokyo, Japan aut NATIONALLICENCE 700 1- Suzuki S. National Institute of Infectious Diseases, Tokyo, Japan aut NATIONALLICENCE 700 1- Nguyen M. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Tran D. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Tran V. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Nguyen H. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Dang D. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Trinh H. Viet-Duc Hospital, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Nguyen T. National Institute of Hygiene and Epidemiology, Yersin Street 1, Hanoi, Vietnam aut NATIONALLICENCE 700 1- Wertheim H. Wellcome Trust Major Overseas Program, Oxford University Clinical Research Unit, Hanoi, Vietnam aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/6(2015-06-01), 1247-1254 0934-9723 34:6<1247 2015 34 10096