caa a22 4500 606155589 CHVBK 20210128100604.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10096-015-2351-8 doi (NATIONALLICENCE)springer-10.1007/s10096-015-2351-8 Ureaplasma parvum and Ureaplasma urealyticum detected with the same frequency among women with and without symptoms of urogenital tract infection [Elektronische Daten] [M. Marovt, D. Keše, T. Kotar, N. Kmet, J. Miljković, B. Šoba, M. Matičič] There is mounting evidence stating that Ureaplasma urealyticum causes non-gonococcal urethritis in males, whereas Ureaplasma parvum does not seem to be of clinical significance. However, the clinical role of U. parvum and U. urealyticum in lower urogenital tract infections in females remains unclear. The aim of the study was to determine the frequency of U. parvum and U. urealyticum among 145 Ureaplasma spp. culture-positive women with symptoms of lower urogenital tract infection (n = 75) and those without (n = 70), and to determine possible associations between the detection of U. parvum and U. urealyticum with selected characteristics. Endocervical, urethral, and vaginal swabs, and first voided urine were obtained. Polymerase chain reaction (PCR) was performed to differentiate ureaplasmas. No significant association between the detection of U. parvum or U. urealyticum and symptom status was found. Significantly more women aged 25 years and younger were infected with U. urealyticum (23.4%) compared to those aged above 25years (9.2%) [odds ratio (OR) 3.0 (1.1; 8.1); p = 0.03] and significantly less women aged 25 years and younger (83.5%) were infected with U. parvum compared to those aged above 25years (95.5%) [OR 0.2 (0.1; 0.9); p = 0.03]. The detection of Chlamydia trachomatis was significantly associated to both U. parvum and U. urealyticum (p = 0.021), and to U. parvum alone with borderline significance (p = 0.063). Although neither U. parvum nor U. urealyticum seem to cause symptoms in females, their role in the female urogenital tract remains unknown, taking into account their ubiquity, possible augmentation of the urogenital microenvironment, and ascending capability to the sterile upper reproductive tract. Springer-Verlag Berlin Heidelberg, 2015 Marovt M. University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia aut Keše D. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia aut Kotar T. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut Kmet N. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut Miljković J. University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia aut Šoba B. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia aut Matičič M. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/6(2015-06-01), 1237-1245 0934-9723 34:6<1237 2015 34 10096 https://doi.org/10.1007/s10096-015-2351-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-015-2351-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Marovt M. University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia aut NATIONALLICENCE 700 1- Keše D. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia aut NATIONALLICENCE 700 1- Kotar T. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut NATIONALLICENCE 700 1- Kmet N. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut NATIONALLICENCE 700 1- Miljković J. University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia aut NATIONALLICENCE 700 1- Šoba B. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia aut NATIONALLICENCE 700 1- Matičič M. Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre Ljubljana, Japljeva 2, 1525, Ljubljana, Slovenia aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/6(2015-06-01), 1237-1245 0934-9723 34:6<1237 2015 34 10096