caa a22 4500 606156437 CHVBK 20210128100608.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10096-014-2247-z doi (NATIONALLICENCE)springer-10.1007/s10096-014-2247-z Bacteremia in previously healthy children in Emergency Departments: clinical and microbiological characteristics and outcome [Elektronische Daten] [B. Gomez, S. Hernandez-Bou, J. Garcia-Garcia, S. Mintegi] A blood culture (BC) is frequently requested in both patients with a suspected occult bacteremia/invasive infection as well as those with certain focal infections. Few data are available on the characteristics of patients in whom a bacteremia is identified in the Pediatric Emergency Department (PED). A prospective multicenter registry was established by the Spanish Pediatric Emergency Society. Epidemiological data, complementary test results, clinical management, and final outcome were recorded. Data from the first three years of the registry were analyzed. A true bacterial pathogen grew in 932 of 65,169 BCs collected [1.43%; 95 % confidence interval (CI) 1.34-1.51%], with 711 of them collected in patients without previously known bacteremia risk factors. Among them, 335 (47.1%) were younger than 1 year old and 467 (65.7%) had a normal Pediatric Assessment Triangle (PAT) on admission. Overall, the most frequently isolated bacterial species was Streptococcus pneumoniae (27.3%; 47.6% among patients with an altered PAT). The main pathogens were Escherichia coli (40.3%) and S. agalactiae (35.7%) among patients younger than 3months, S. pneumoniae among patients 3-60months old (40.0%), and S. aureus (31.9%) among patients over 60months of age. Neisseria meningitidis was the leading cause of sepsis in patients older than 3months. Eight patients died; none of them had a pneumococcal bacteremia and all had abnormal PAT findings on admission. S. pneumoniae is the main cause of bacteremia in patients without bacteremia risk factors who attended Spanish PEDs. Age and general appearance influence the frequency of each bacterial species. General appearance also influences the associated mortality. Springer-Verlag Berlin Heidelberg, 2014 Gomez B. Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Spain aut Hernandez-Bou S. Pediatrics and Pediatric Emergency Departments, Hospital Sant Joan de Déu Barcelona, Universitat de Barcelona, Barcelona, Spain aut Garcia-Garcia J. Pediatrics and Pediatric Emergency Departments, Hospital Sant Joan de Déu Barcelona, Universitat de Barcelona, Barcelona, Spain aut Mintegi S. Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Spain aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/3(2015-03-01), 453-460 0934-9723 34:3<453 2015 34 10096 https://doi.org/10.1007/s10096-014-2247-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-014-2247-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gomez B. Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Spain aut NATIONALLICENCE 700 1- Hernandez-Bou S. Pediatrics and Pediatric Emergency Departments, Hospital Sant Joan de Déu Barcelona, Universitat de Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Garcia-Garcia J. Pediatrics and Pediatric Emergency Departments, Hospital Sant Joan de Déu Barcelona, Universitat de Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Mintegi S. Pediatric Emergency Department, Cruces University Hospital, University of the Basque Country, Bilbao, Spain aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/3(2015-03-01), 453-460 0934-9723 34:3<453 2015 34 10096