caa a22 4500 60615695X CHVBK 20210128100611.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10096-014-2273-x doi (NATIONALLICENCE)springer-10.1007/s10096-014-2273-x Is Streptococcus bovis a urinary pathogen? [Elektronische Daten] [M. Matesanz, D. Rubal, I. Iñiguez, R. Rabuñal, F. García-Garrote, A. Coira, M. García-País, J. Pita, A. Rodriguez-Macias, M. López-Álvarez, M. Alonso, J. Corredoira] The Streptococcus bovis group (SBG) comprises several microorganisms associated with human infections. They have been associated with bacteremia, endocarditis, biliary tract infection, meningitis, and colorectal cancer, but their role as urinary pathogens is not well known. The objective of this investigation was to discover the incidence and clinical significance of the bacteriuria associated with this complex. A retrospective analysis of all adult patients with bacteriuria caused by SBG during the period 1995-2012 was carried out. During the study period, SBG was isolated in 153 adult patients, who had a mean age of 67years, most of them being women (80%). Most of our patients (65%) had some underlying disease, with urologic disease being the most common (37%), followed by diabetes mellitus (27%) and neurologic disease (25%). Among the 88 patients in whom we were able to correctly assess symptoms, 45% had asymptomatic bacteriuria, 35% had lower urinary tract infection, and 20% had upper urinary tract infection. In 14 cases (9%), SBG was also isolated in blood cultures. Most of the isolates of SBG (72%) were S. gallolyticus subsp. pasteurianus. All isolates were susceptible to penicillin, 98% to nitrofurantoin, and 77% to fosfomycin. Although SBG bacteriuria is uncommon, it should not always be taken as a contaminant, mainly when S. pasteurianus is isolated, because it may cause urinary tract infections and, occasionally, sepsis, whereas when S. gallolyticus is isolated from urine, it may be a marker of underlying endocarditis and colorectal cancer. Springer-Verlag Berlin Heidelberg, 2014 Matesanz M. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut Rubal D. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut Iñiguez I. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut Rabuñal R. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut García-Garrote F. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut Coira A. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut García-País M. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut Pita J. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut Rodriguez-Macias A. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut López-Álvarez M. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut Alonso M. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut Corredoira J. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/4(2015-04-01), 719-725 0934-9723 34:4<719 2015 34 10096 https://doi.org/10.1007/s10096-014-2273-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-014-2273-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Matesanz M. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Rubal D. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Iñiguez I. Department of Internal Medicine, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Rabuñal R. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut NATIONALLICENCE 700 1- García-Garrote F. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Coira A. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- García-País M. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut NATIONALLICENCE 700 1- Pita J. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Rodriguez-Macias A. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- López-Álvarez M. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut NATIONALLICENCE 700 1- Alonso M. Department of Clinical Microbiology, Hospital Lucus Augusti, Lugo, Spain aut NATIONALLICENCE 700 1- Corredoira J. Infectious Disease Unit, Hospital Lucus Augusti, San Cibrao s/n, 27003, Lugo, Spain aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/4(2015-04-01), 719-725 0934-9723 34:4<719 2015 34 10096