caa a22 4500 606157077 CHVBK 20210128100611.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10096-014-2292-7 doi (NATIONALLICENCE)springer-10.1007/s10096-014-2292-7 Does cerumen have a risk for transmission of HIV? [Elektronische Daten] [F. Hanege, M. Kalcioglu, F. Sargin, Z. Cetinkaya, M. Tekin, H. Vahaboglu] Human immunodeficiency virus (HIV) is mainly transmitted via sexual activity, mother-to-child transmission, and contact with body fluids, such as saliva and semen. Cerumen, however, has not been investigated for its capability to transmit HIV. The purpose of this study was to evaluate the potential of cerumen for transmission of HIV infection. This study was conducted among 42 treatment-naive HIV-infected patients with positive HIV RNA and 27 HIV-infected patients with negative HIV RNA receiving antiviral treatment. Simultaneous blood samples were studied as positive controls. Sixty-nine prospectively collected cerumen specimens were analyzed for the presence of HIV RNA by real-time polymerase chain reaction (PCR). None of the 69 cerumen specimens were positive for HIV RNA. These results conclude that cerumen in HIV-positive patients with or without antiretroviral therapy (ART) carry only an insignificant risk of transmission. However, standard infection control precautions should be applied carefully in all examinations and surgical operations of the ears. Springer-Verlag Berlin Heidelberg, 2014 Hanege F. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut Kalcioglu M. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut Sargin F. Department of Infectious Diseases and Clinical Microbiology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut Cetinkaya Z. Department of Microbiology and Clinical Microbiology, Goztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut Tekin M. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut Vahaboglu H. Department of Infectious Diseases and Clinical Microbiology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/4(2015-04-01), 789-793 0934-9723 34:4<789 2015 34 10096 https://doi.org/10.1007/s10096-014-2292-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-014-2292-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hanege F. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Kalcioglu M. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Sargin F. Department of Infectious Diseases and Clinical Microbiology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Cetinkaya Z. Department of Microbiology and Clinical Microbiology, Goztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Tekin M. Department of Otorhinolaryngology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Vahaboglu H. Department of Infectious Diseases and Clinical Microbiology, Göztepe Training and Research Hospital, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/4(2015-04-01), 789-793 0934-9723 34:4<789 2015 34 10096