caa a22 4500 606157573 CHVBK 20210128100614.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s10096-014-2306-5 doi (NATIONALLICENCE)springer-10.1007/s10096-014-2306-5 General and advanced diagnostic tools to detect Mycobacterium tuberculosis and their drug susceptibility: a review [Elektronische Daten] [Md. Gazi, Md. Islam, Mohammad Kibria, Z. Mahmud] The global control of tuberculosis remains a great challenge from the standpoint of diagnosis, detection of drug resistance, and treatment, because treatment can only be initiated when infection is detected, and is guided by the results of antimicrobial susceptibility testing. To a large extent, non-molecular, immunological, and other biochemical methods are refinements or modifications of conventional methods, with the primary goal of providing more rapid test results. In contrast, molecular methods use novel technologies to detect the presence of Mycobacterium tuberculosis complex and genes conferring drug resistance. As a group, molecular technologies offer the greatest potential for laboratories in resource-rich countries because they have the highest sensitivity and specificity. In resource-poor settings, continued development of affordable, sensitive, and specific diagnostic tools will be required, where the incidence of disease is highest. Springer-Verlag Berlin Heidelberg, 2015 Gazi Md Parasitology Laboratory, International Centre for Diarrheal Disease Research, 1212, Dhaka, Bangladesh aut Islam Md International Max Planck Research School, 37075, Göttingen, Germany aut Kibria Mohammad Parasitology Laboratory, International Centre for Diarrheal Disease Research, 1212, Dhaka, Bangladesh aut Mahmud Z. Department of Biochemistry and Molecular Biology, University of Dhaka, 1000, Dhaka, Bangladesh aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/5(2015-05-01), 851-861 0934-9723 34:5<851 2015 34 10096 https://doi.org/10.1007/s10096-014-2306-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-014-2306-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gazi Md Parasitology Laboratory, International Centre for Diarrheal Disease Research, 1212, Dhaka, Bangladesh aut NATIONALLICENCE 700 1- Islam Md International Max Planck Research School, 37075, Göttingen, Germany aut NATIONALLICENCE 700 1- Kibria Mohammad Parasitology Laboratory, International Centre for Diarrheal Disease Research, 1212, Dhaka, Bangladesh aut NATIONALLICENCE 700 1- Mahmud Z. Department of Biochemistry and Molecular Biology, University of Dhaka, 1000, Dhaka, Bangladesh aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/5(2015-05-01), 851-861 0934-9723 34:5<851 2015 34 10096