caa a22 4500 606157956 CHVBK 20210128100616.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10096-014-2238-0 doi (NATIONALLICENCE)springer-10.1007/s10096-014-2238-0 Validation of a severity grading score (SGS) system for predicting the course of disease and mortality in patients with Crimean-Congo hemorrhagic fever (CCHF) [Elektronische Daten] [M. Bakır, M. Gözel, İ. Köksal, Z. Aşık, Ö. Günal, H. Yılmaz, A. But, G. Yılmaz, A. Engin] We aimed to validate a severity grading score (SGS) system for predicting the course of disease and fatality in Crimean-Congo hemorrhagic fever (CCHF). This SGS was established using several variables that were assumed to be associated with mortality and had clinical importance. We included patients diagnosed with CCHF from different centers. Patients who had symptoms of CCHF for <5days were included. The patients were grouped into three categories according to mortality risk. An SGS ≤4 showed no association with mortality [n = 323 (79.9% of the total study population), and all survived]. An SGS between 5 and 8 points was classified into the intermediate risk group (20%), and 14 of 70 patients in this group died. An SGS ≥9 was classified as the high risk of mortality group and 11 of 11 patients in this group died (p = 0.001). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for an SGS >9 points at admission were 96, 100, 97, 100, and 44%, respectively. This SGS system may help appropriate the triage of patients, decrease the cost of treatment, and improve the functionality of healthcare staff. The present study is the first investigation about the validation of an SGS system in patients with CCHF. Springer-Verlag Berlin Heidelberg, 2014 Bakır M. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut Gözel M. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut Köksal İ. Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey aut Aşık Z. Department of Infectious Diseases, Tokat State Hospital, Tokat, Turkey aut Günal Ö. Department of Infectious Diseases and Clinical Microbiology, Gaziosmanpasa University, School of Medicine, Tokat, Turkey aut Yılmaz H. Department of Infectious Diseases and Clinical Microbiology, 19 Mayıs University, School of Medicine, Samsun, Turkey aut But A. Department of Infectious Diseases and Clinical Ankara Numune Training and Research Hospital, Ankara, Turkey aut Yılmaz G. Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey aut Engin A. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/2(2015-02-01), 325-330 0934-9723 34:2<325 2015 34 10096 https://doi.org/10.1007/s10096-014-2238-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-014-2238-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bakır M. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut NATIONALLICENCE 700 1- Gözel M. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut NATIONALLICENCE 700 1- Köksal İ. Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey aut NATIONALLICENCE 700 1- Aşık Z. Department of Infectious Diseases, Tokat State Hospital, Tokat, Turkey aut NATIONALLICENCE 700 1- Günal Ö. Department of Infectious Diseases and Clinical Microbiology, Gaziosmanpasa University, School of Medicine, Tokat, Turkey aut NATIONALLICENCE 700 1- Yılmaz H. Department of Infectious Diseases and Clinical Microbiology, 19 Mayıs University, School of Medicine, Samsun, Turkey aut NATIONALLICENCE 700 1- But A. Department of Infectious Diseases and Clinical Ankara Numune Training and Research Hospital, Ankara, Turkey aut NATIONALLICENCE 700 1- Yılmaz G. Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University, School of Medicine, Trabzon, Turkey aut NATIONALLICENCE 700 1- Engin A. Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University, School of Medicine, 58140, Sivas, Turkey aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/2(2015-02-01), 325-330 0934-9723 34:2<325 2015 34 10096