caa a22 4500 606157980 CHVBK 20210128100616.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s10096-015-2464-0 doi (NATIONALLICENCE)springer-10.1007/s10096-015-2464-0 Gut microbiota modulate the immune effect against hepatitis B virus infection [Elektronische Daten] [D. Xu, Y. Huang, J. Wang] The immunological mechanisms by which hepatitis B virus (HBV) initiates and maintains acute or chronic infection, even the formation of cirrhosis and hepatocellular carcinoma, are still undefined. An increasing number of studies have shown that intestinal flora regulate immune homeostasis, and, thus, protect the immunologic function against hepatitis virus infection. In this article, we discuss gut microbiota and its potential immune effects against HBV infection. It may provide a novel insight into the pathogenesis of HBV infection, as well as a potential therapeutic target to HBV-related disease. Springer-Verlag Berlin Heidelberg, 2015 Xu D. Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China aut Huang Y. Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China aut Wang J. Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Avenue, 430030, Wuhan, China aut European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/11(2015-11-01), 2139-2147 0934-9723 34:11<2139 2015 34 10096 https://doi.org/10.1007/s10096-015-2464-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10096-015-2464-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Xu D. Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China aut NATIONALLICENCE 700 1- Huang Y. Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China aut NATIONALLICENCE 700 1- Wang J. Department of Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Avenue, 430030, Wuhan, China aut NATIONALLICENCE 773 0- European Journal of Clinical Microbiology & Infectious Diseases Springer Berlin Heidelberg 34/11(2015-11-01), 2139-2147 0934-9723 34:11<2139 2015 34 10096