caa a22 4500 606162909 CHVBK 20210128100641.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s11062-015-9526-x doi (NATIONALLICENCE)springer-10.1007/s11062-015-9526-x Improvement of Regional Cerebral Blood Flow After Stimulation of the Nucl. Fastigius in Cerebral Infarction Patients [Elektronische Daten] [Q. Li, J. Yang] Experimental studies reported that focal stimulation of the nucl. fastigius (fastigial nucleus stimulation, FNS) increases regional cerebral blood flow (rCBF) and ameliorates disorders of cerebral blood circulation. The aim of our study was to examine the effect of FNS on rCBF in cerebral infarction patients and to estimate correlation of the respective effect with prognosis and treatment. The rCBF of 20 cerebral infarction patients was measured before and after FNS using single-photon emission computed tomography (SPECT), and the data were subjected to semiquantitative analysis. Results of the neural ability defect test were used to evaluate prognosis. In the above patients, different levels of decreased rCBF were observed. Focal FNS noticeably ameliorated disorders of scirculation in both the infarction area and the corresponding contralateral cerebral area (P < 0.05). The SPECT images showed that the improvement of rCBF was more evident in the central region of the lesion than in the surrounding area. Thus, it was demonstrated that FNS treatment enhances rCBF, which is followed by the improvement of clinical symptoms in cerebral infarction patients. Springer Science+Business Media New York, 2015 cerebral infarction nationallicence regional cerebral blood flow (rCBF) nationallicence fastigial nucleus nationallicence electronic focal stimulation nationallicence single-photon emission computed tomography (SPECT) nationallicence Li Q. Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China aut Yang J. Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China aut Neurophysiology Springer US; http://www.springer-ny.com 47/3(2015-06-01), 234-237 0090-2977 47:3<234 2015 47 11062 https://doi.org/10.1007/s11062-015-9526-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11062-015-9526-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Li Q. Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China aut NATIONALLICENCE 700 1- Yang J. Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China aut NATIONALLICENCE 773 0- Neurophysiology Springer US; http://www.springer-ny.com 47/3(2015-06-01), 234-237 0090-2977 47:3<234 2015 47 11062