caa a22 4500 606171037 CHVBK 20210128100720.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10728-013-0259-y doi (NATIONALLICENCE)springer-10.1007/s10728-013-0259-y Hens Kristien Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Maastricht University, P.O. Box 616, 6200, Maastricht, The Netherlands aut To Transfer or Not to Transfer: The Case of Comprehensive Chromosome Screening of the In Vitro Embryo [Elektronische Daten] [Kristien Hens] The screening of in vitro embryos resulting from in vitro fertilization (IVF) treatment for chromosomal abnormalities (aneuploidies) has as a primary aim to help patients achieve a successful pregnancy. Most IVF centers will not transfer aneuploid embryos, as they have an enhanced risk of leading to implantation failure and miscarriage. However, some aneuploidies, such as trisomy-21, can lead to viable pregnancies and to children with a variable health prognosis, and some prospective parents may request transfer of such embryos. I present two cases where the testing for and detection of trisomy-21 can lead to conflicts between IVF professionals and patients and argue that in most such cases respect for choices of patients should prevail. Springer Science+Business Media New York, 2013 Embryo nationallicence Ethics nationallicence Chromosomes nationallicence Aneuploidy nationallicence Trisomy-21 nationallicence Down syndrome nationallicence Preimplantation genetic screening nationallicence Preimplantation genetic diagnosis nationallicence Health Care Analysis Springer US; http://www.springer-ny.com 23/2(2015-06-01), 197-206 1065-3058 23:2<197 2015 23 10728 https://doi.org/10.1007/s10728-013-0259-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10728-013-0259-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Hens Kristien Department of Health, Ethics and Society, Faculty of Health, Medicine and Life Sciences, Maastricht University, P.O. Box 616, 6200, Maastricht, The Netherlands aut NATIONALLICENCE 773 0- Health Care Analysis Springer US; http://www.springer-ny.com 23/2(2015-06-01), 197-206 1065-3058 23:2<197 2015 23 10728