caa a22 4500 606171096 CHVBK 20210128100721.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10140-014-1242-0 doi (NATIONALLICENCE)springer-10.1007/s10140-014-1242-0 Hereditary angioedema: imaging manifestations and clinical management [Elektronische Daten] [Mandip Gakhal, Gregory Marcotte] Hereditary angioedema is a genetic disorder typically related to insufficient or dysfunctional C1-esterase inhibitor. Patients present with episodic swelling of various body parts, such as the face, neck, bowel, genitals, and extremities. Acute or severe symptoms can lead to patients presenting to the emergency room, particularly when the neck and abdominopelvic regions are affected, which is often accompanied by radiologic imaging evaluation. Patients with hereditary angioedema can pose a diagnostic challenge for emergency department physicians and radiologists at initial presentation, and the correct diagnosis may be missed or delayed, due to lack of clinical awareness of the disease or lack of its consideration in the radiologic differential diagnosis. Timely diagnosis of hereditary angioedema and rapid initiation of appropriate therapy can avoid potentially life-threatening complications. This article focuses on the spectrum of common and characteristic acute imaging manifestations of hereditary angioedema and provides an update on important recent developments in its clinical management and treatment. Am Soc Emergency Radiol, 2014 Hereditary angioedema nationallicence Diagnostic imaging nationallicence Computed tomography nationallicence Magnetic resonance imaging nationallicence Angioedema nationallicence Treatment nationallicence Therapy nationallicence Gakhal Mandip Christiana Care Health System, 4755 Ogletown-Stanton Rd, 19718, Newark, DE, USA aut Marcotte Gregory Christiana Care Health System, 4755 Ogletown-Stanton Rd, 19718, Newark, DE, USA aut Emergency Radiology Springer Berlin Heidelberg 22/1(2015-02-01), 83-90 1070-3004 22:1<83 2015 22 10140 https://doi.org/10.1007/s10140-014-1242-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10140-014-1242-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gakhal Mandip Christiana Care Health System, 4755 Ogletown-Stanton Rd, 19718, Newark, DE, USA aut NATIONALLICENCE 700 1- Marcotte Gregory Christiana Care Health System, 4755 Ogletown-Stanton Rd, 19718, Newark, DE, USA aut NATIONALLICENCE 773 0- Emergency Radiology Springer Berlin Heidelberg 22/1(2015-02-01), 83-90 1070-3004 22:1<83 2015 22 10140