caa a22 4500 606172092 CHVBK 20210128100726.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10140-014-1230-4 doi (NATIONALLICENCE)springer-10.1007/s10140-014-1230-4 High pitch, low voltage dual source CT pulmonary angiography: assessment of image quality and diagnostic acceptability with hybrid iterative reconstruction [Elektronische Daten] [Patrick McLaughlin, T. Liang, M. Homiedan, L. Louis, T. O'Connell, Karl Krzymyk, S. Nicolaou, J. Mayo] Increased use of CT Pulmonary angiography in suspected pulmonary embolism (PE) has driven research to minimize radiation dose while maintaining image quality and diagnostic accuracy. Following institutional review board approval, we performed a retrospective comparison study in patients with suspected PE. Patients were scanned using an ultra high pitch dual source technique (pitch = 2.6) using 120kV (SVCTPA) (n = 54) or 100kV (RV-CTPA) (n = 52). SV-CTPA images were reconstructed using filtered back projection (SV-wFBP) and RV-CTPA images were reconstructed using both FBP (RV-wFBP) and Iterative Reconstruction (RV-IR). Comparison of radiation dose, diagnostic ability, subjective image noise, quality, and sharpness, diagnostic agreement, signal to noise (SNR) and contrast to noise ratios (CNR) were performed. Mean effective dose was 2.56 ± 0.19mSv for the RV protocol compared to 5.36 ± 0.60mSv for the SV. The RV-CTPA protocol resulted in a mean DLP reduction of 52% and mean CTDI reduction of 51%. Pulmonary artery SNR and CNR were significantly higher on RV-IR images than SV-wFBP (p = 0.007, p = 0.003). Mean subjective image noise, quality and sharpness scores did not differ significantly between the SV-wFBP and RVIR images (p > 0.05). Subjective quality scores were significantly better for the RV-IR group compared to the RV-wFBP group (p < 0.001). Agreement between readers for presence or absence of pulmonary emboli on RV-IR images was almost perfect (κ = 0.891, p < 0.001). Iterative reconstruction complements ultra high pitch dual source CTPA examinations acquired using a reduced voltage resulting in higher mean pulmonary artery SNR and CNR when compared to both RV-wFBP and SV-CTPA. Am Soc Emergency Radiol, 2014 Iterative reconstruction nationallicence Computed tomography nationallicence Pulmonary embolism nationallicence CTPA nationallicence Dual source CT nationallicence Radiation dose nationallicence McLaughlin Patrick Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Liang T. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Homiedan M. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Louis L. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut O'Connell T. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Krzymyk Karl CT Research Collaborations, Siemens Healthcare, Forchheim, Germany aut Nicolaou S. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Mayo J. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut Emergency Radiology Springer Berlin Heidelberg 22/2(2015-04-01), 117-123 1070-3004 22:2<117 2015 22 10140 https://doi.org/10.1007/s10140-014-1230-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10140-014-1230-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McLaughlin Patrick Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Liang T. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Homiedan M. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Louis L. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- O'Connell T. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Krzymyk Karl CT Research Collaborations, Siemens Healthcare, Forchheim, Germany aut NATIONALLICENCE 700 1- Nicolaou S. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Mayo J. Department of Radiology, Vancouver General Hospital, V5Z 1M9, Vancouver, BC, Canada aut NATIONALLICENCE 773 0- Emergency Radiology Springer Berlin Heidelberg 22/2(2015-04-01), 117-123 1070-3004 22:2<117 2015 22 10140