caa a22 4500 606176896 CHVBK 20210128100749.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00018-015-1837-y doi (NATIONALLICENCE)springer-10.1007/s00018-015-1837-y Proteogenomics: emergence and promise [Elektronische Daten] [Sam Faulkner, Matthew Dun, Hubert Hondermarck] Proteogenomics, or the integration of proteomics with genomics and transcriptomics, is emerging as the next step towards a unified understanding of cellular functions. Looking globally and simultaneously at gene structure, RNA expression, protein synthesis and post-translational modifications have become technically feasible and offer a new perspective to molecular processes. Recent publications have highlighted the value of proteogenomics in oncology for defining the molecular signature of human tumors, and translation to other areas of biomedicine and life sciences is anticipated. This mini-review will discuss recent developments, challenges and perspectives in proteogenomics. Springer Basel, 2015 Omics nationallicence Proteomics nationallicence Transcriptomics nationallicence Genomics nationallicence Metabolomics nationallicence Faulkner Sam Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut Dun Matthew Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut Hondermarck Hubert Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut Cellular and Molecular Life Sciences Springer Basel 72/5(2015-03-01), 953-957 1420-682X 72:5<953 2015 72 18 https://doi.org/10.1007/s00018-015-1837-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 editorial jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00018-015-1837-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Faulkner Sam Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut NATIONALLICENCE 700 1- Dun Matthew Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut NATIONALLICENCE 700 1- Hondermarck Hubert Faculty of Health and Medicine, School of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Life Science Building, University of Newcastle, NSW 2308, Callaghan, Australia aut NATIONALLICENCE 773 0- Cellular and Molecular Life Sciences Springer Basel 72/5(2015-03-01), 953-957 1420-682X 72:5<953 2015 72 18