caa a22 4500 60617804X CHVBK 20210128100754.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s11136-014-0854-x doi (NATIONALLICENCE)springer-10.1007/s11136-014-0854-x Predictors of health-related quality of life perceived by end-stage renal disease patients under online hemodiafiltration [Elektronische Daten] [Alexandra Moura, José Madureira, Pablo Alija, João Fernandes, José Oliveira, Martin Lopez, Madalena Filgueiras, Leonilde Amado, Maria Sameiro-Faria, Vasco Miranda, Edgar Mesquita, Alice Santos-Silva, Elísio Costa] Purpose: Patients' perception of health-related quality of life (HRQOL) is a consistent and powerful predictor of the outcome of end-stage renal disease (ESRD) patients under dialysis. This study aims to identify factors that could affect the HRQOL of ESRD patients under online hemodiafiltration (OL-HDF). Methods: We evaluated 322 ESRD patients under OL-HDF (59.63% males; 64.9±14.3years old) from five dialysis units in the north of Portugal. Socio-demographic data, comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patients records. Patient's reported HRQOL score was assessed by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF). Results: ESRD patients showed a mean (±SD) of 53.17% (±15.31%) in SF-36 total score, 50.17% (±9.51%) in the SF-36 mental component summary (MCS) and 49.75% (±9.44%) in the SF-36 physical component summary (PCS). Red cell distribution width (RDW), feminine gender and diabetes were found as significant predictors of SF-36 total score of HRQOL, which accounts for 12% of the total explained variance. Patient satisfaction, RDW, body mass index and gender were identified as predictors for the PCS, which accounts for 22% of total explained variance. Furthermore, patient satisfaction and dry weight were found as predictors for MCS. These predictors accounted for 28% of the total explained variance. Conclusions: Our results showed that the coexistence of diabetes, gender and erythropoietic disturbances are predictors of HRQOL in patients under OL-HDF and suggest that more attention should be given to woman patients, to the improvement of anemia and to diabetic patients, who are more prone to perceive a worst HRQOL. Springer International Publishing Switzerland, 2014 Online hemodiafiltration nationallicence Dialysis nationallicence Health-related quality of life nationallicence Kidney Disease Quality of Life-Short Form nationallicence Predictors nationallicence Moura Alexandra Instituto de Ciências da Saúde, Universidade Católica Portuguesa, Porto, Portugal aut Madureira José Clínica de Hemodiálise NefroServe, Barcelos, Portugal aut Alija Pablo Clínica de Hemodiálise NefroServe, Barcelos, Portugal aut Fernandes João Clínica de Hemodiálise NefroServe, Viana do Castelo, Portugal aut Oliveira José Centro Hospitalar do Porto, Porto, Portugal aut Lopez Martin Clínica de Hemodiálise de Felgueira, Felgueiras, Portugal aut Filgueiras Madalena Clínica de Hemodiálise de Gondomar, Gondomar, Portugal aut Amado Leonilde Clínica de Hemodiálise NephroCare, Maia, Portugal aut Sameiro-Faria Maria Clínica de Hemodiálise NephroCare, Maia, Portugal aut Miranda Vasco Clínica de Hemodiálise NephroCare, Maia, Portugal aut Mesquita Edgar Núcleo de Estudantes de Estatística, Universidade do Minho, Braga, Portugal aut Santos-Silva Alice Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal aut Costa Elísio Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal aut Quality of Life Research Springer International Publishing 24/6(2015-06-01), 1327-1335 0962-9343 24:6<1327 2015 24 11136 https://doi.org/10.1007/s11136-014-0854-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0854-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Moura Alexandra Instituto de Ciências da Saúde, Universidade Católica Portuguesa, Porto, Portugal aut NATIONALLICENCE 700 1- Madureira José Clínica de Hemodiálise NefroServe, Barcelos, Portugal aut NATIONALLICENCE 700 1- Alija Pablo Clínica de Hemodiálise NefroServe, Barcelos, Portugal aut NATIONALLICENCE 700 1- Fernandes João Clínica de Hemodiálise NefroServe, Viana do Castelo, Portugal aut NATIONALLICENCE 700 1- Oliveira José Centro Hospitalar do Porto, Porto, Portugal aut NATIONALLICENCE 700 1- Lopez Martin Clínica de Hemodiálise de Felgueira, Felgueiras, Portugal aut NATIONALLICENCE 700 1- Filgueiras Madalena Clínica de Hemodiálise de Gondomar, Gondomar, Portugal aut NATIONALLICENCE 700 1- Amado Leonilde Clínica de Hemodiálise NephroCare, Maia, Portugal aut NATIONALLICENCE 700 1- Sameiro-Faria Maria Clínica de Hemodiálise NephroCare, Maia, Portugal aut NATIONALLICENCE 700 1- Miranda Vasco Clínica de Hemodiálise NephroCare, Maia, Portugal aut NATIONALLICENCE 700 1- Mesquita Edgar Núcleo de Estudantes de Estatística, Universidade do Minho, Braga, Portugal aut NATIONALLICENCE 700 1- Santos-Silva Alice Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal aut NATIONALLICENCE 700 1- Costa Elísio Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/6(2015-06-01), 1327-1335 0962-9343 24:6<1327 2015 24 11136