caa a22 4500 606178201 CHVBK 20210128100755.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s11136-014-0864-8 doi (NATIONALLICENCE)springer-10.1007/s11136-014-0864-8 Cross-cultural measurement equivalence of the EQ-5D-5L items for English-speaking Asians in Singapore [Elektronische Daten] [N. Luo, Y. Wang, C. How, K. Wong, L. Shen, E. Tay, J. Thumboo, M. Herdman] Purpose: To investigate how the response labels of the 5-level EQ-5D (EQ-5D-5L) items are interpreted and used by English-speaking Chinese and non-Chinese Singaporeans, as a means to assessing whether those items are cross-culturally equivalent health-status measures in this Asian population. Methods: In face-to-face interviews, Chinese, Malay and Indian visitors to a primary care institution in Singapore were asked to rate the relative severity conveyed by EQ-5D-5L response labels, each containing the keyword of ‘no(t),' ‘slight(ly),' ‘moderate(ly),' ‘severe(ly),' or ‘unable'/‘extreme(ly),' using a 0-100 numerical rating scale. Participants were also asked to describe 25 hypothetical health states using the EQ-5D-5L response labels. Differences between Chinese and Malay/Indian participants in label interpretation and selection were examined using multivariate regression analysis to adjust for participant characteristics. Results: The differences in adjusted mean severity scores for individual EQ-5D-5L labels between Chinese (n=148) and non-Chinese (Malay: n=53; Indian: n=56) participants ranged from 0.0 to 9.0. The relative severity of the labels to the participants supported the ordinality of the EQ-5D-5L response labels and was similar across ethnic groups. Chinese and non-Chinese participants selected similar response labels to describe each hypothetical health state, with the adjusted odds ratios of selecting any type of the five response labels for non-Chinese versus Chinese participants ranging from 0.92 to 1.15 (p>0.05 for all). Conclusions: The EQ-5D-5L items are likely to generate equivalent health outcomes between English-speaking Chinese and non-Chinese Singaporeans. Springer International Publishing Switzerland, 2014 EQ-5D nationallicence Cross-cultural equivalence nationallicence Response scaling nationallicence Luo N. Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Block MD1, 117549, Singapore, Singapore aut Wang Y. Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA aut How C. SingHealth Polyclinics, Singapore, Singapore aut Wong K. Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Block MD1, 117549, Singapore, Singapore aut Shen L. Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore aut Tay E. SingHealth Polyclinics, Singapore, Singapore aut Thumboo J. Singapore General Hospital and Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore aut Herdman M. Insight Consulting and Research, Mataro, Spain aut Quality of Life Research Springer International Publishing 24/6(2015-06-01), 1565-1574 0962-9343 24:6<1565 2015 24 11136 https://doi.org/10.1007/s11136-014-0864-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0864-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Luo N. Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Block MD1, 117549, Singapore, Singapore aut NATIONALLICENCE 700 1- Wang Y. Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- How C. SingHealth Polyclinics, Singapore, Singapore aut NATIONALLICENCE 700 1- Wong K. Saw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Block MD1, 117549, Singapore, Singapore aut NATIONALLICENCE 700 1- Shen L. Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore aut NATIONALLICENCE 700 1- Tay E. SingHealth Polyclinics, Singapore, Singapore aut NATIONALLICENCE 700 1- Thumboo J. Singapore General Hospital and Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore aut NATIONALLICENCE 700 1- Herdman M. Insight Consulting and Research, Mataro, Spain aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/6(2015-06-01), 1565-1574 0962-9343 24:6<1565 2015 24 11136